Mature hsa-miR-186-5p

• Accession: MIMAT0000456
• Description: hsa-miR-186-5p mature miRNA
• Hairpins:
  • hsa-mir-186
• Sequence: CAAAGAAUUCUCCUUUUGGGCU
• Evidence: experimental ; cloned [1-3]

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Qualifier	GO term	Evidence	Reference	Annotation Extension
acts_upstream_of	GO:0032410 negative regulation of transporter activity	ECO:0000315 mutant phenotype evidence used in manual assertion	PMID:26626440	has_input UniProtKB:P08183
acts_upstream_of	GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	ECO:0000314 direct assay evidence used in manual assertion	PMID:27714074
acts_upstream_of	GO:1902430 negative regulation of amyloid-beta formation	ECO:0000314 direct assay evidence used in manual assertion	PMID:25100943	has_output UniProtKB:P05067-PRO_0000000093
acts_upstream_of	GO:1905700 negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	ECO:0000315 mutant phenotype evidence used in manual assertion	PMID:26626440
acts_upstream_of_or_within	GO:0010629 negative regulation of gene expression	ECO:0000315 mutant phenotype evidence used in manual assertion	PMID:26626440	has_input UniProtKB:P09211
enables	GO:0003730 mRNA 3'-UTR binding	ECO:0000314 direct assay evidence used in manual assertion	PMID:25100943
enables	GO:0003730 mRNA 3'-UTR binding	ECO:0000314 direct assay evidence used in manual assertion	PMID:26626440	has_input UniProtKB:P08183
enables	GO:0003730 mRNA 3'-UTR binding	ECO:0000314 direct assay evidence used in manual assertion	PMID:27714074
enables	GO:1903231 mRNA base-pairing translational repressor activity	ECO:0000314 direct assay evidence used in manual assertion	PMID:25100943	has_input UniProtKB:Q92542
enables	GO:1903231 mRNA base-pairing translational repressor activity	ECO:0000314 direct assay evidence used in manual assertion	PMID:26626440	has_input UniProtKB:P08183
enables	GO:1903231 mRNA base-pairing translational repressor activity	ECO:0000314 direct assay evidence used in manual assertion	PMID:27714074	has_input UniProtKB:P10636
involved_in	GO:0035195 miRNA-mediated post-transcriptional gene silencing	ECO:0000314 direct assay evidence used in manual assertion	PMID:25100943	has_input UniProtKB:Q92542
involved_in	GO:0035195 miRNA-mediated post-transcriptional gene silencing	ECO:0000314 direct assay evidence used in manual assertion	PMID:26626440	has_input UniProtKB:P08183
involved_in	GO:0035195 miRNA-mediated post-transcriptional gene silencing	ECO:0000314 direct assay evidence used in manual assertion	PMID:27714074	has_input UniProtKB:P10636
located_in	GO:0005615 extracellular space	ECO:0007005 high throughput direct assay evidence used in manual assertion	PMID:26646931	part_of UBERON:0001969