Stem-loop sequence mmu-mir-23b

Accession

MI0000141

Symbol

MGI:Mir23b

Description

Mus musculus miR-23b stem-loop

Gene family

MIPF0000027; mir-23

Stem-loop

  c   u   --          -  c      gugacu 
gg ugc ugg  guuccuggca ug ugauuu      u
|| ||| |||  |||||||||| || ||||||       
cc acg acc  uagggaccgu ac acuaaa      g
  a   c   au          u  -      auuaga 

Deep sequencing

841134 reads, 97 experiments

Genome context

• Coordinates (GRCm38): chr13: 63300484-63300557 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000076332 ; AC130827.2-002; intron 3

  ENSMUST00000083665 ; Mir23b-201; exon 1

  ENSMUST00000159152 ; 2010111I01Rik-002; intron 3

  ENSMUST00000021911 ; 2010111I01Rik-201; intron 15

Clustered miRNAs

< 10kb from mmu-mir-23b

• mmu-mir-23b: chr13: 63300484-63300557 [+]
• mmu-mir-27b: chr13: 63300712-63300784 [+]
• mmu-mir-3074-1: chr13: 63301199-63301283 [-]
• mmu-mir-24-1: chr13: 63301208-63301275 [+]

Database links

• EMBL: AJ459714;MMU459714
• ENTREZGENE: 387217;Mir23b
• MGI: 2676898;Mir23b

Mature sequence mmu-miR-23b-5p

• Accession: MIMAT0016980
• Previous IDs: mmu-miR-23b*
• Sequence: 9 - ggguuccuggcaugcugauuu - 29
• Deep sequencing: 15824 reads, 69 experiments
• Evidence: experimental; Solexa [6]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-23b-5p
  • MIRDB:mmu-miR-23b-5p
  • RNA22-MMU:mmu-miR-23b-5p

Mature sequence mmu-miR-23b-3p

• Accession: MIMAT0000125
• Previous IDs: mmu-miR-23b
• Sequence: 46 - aucacauugccagggauuacc - 66
• Deep sequencing: 757959 reads, 82 experiments
• Evidence: experimental; cloned [1,3-4], Solexa [5-6]
• Validated targets:
  • TARBASE:mmu-miR-23b-3p
• Predicted targets:
  • DIANA-MICROT:mmu-miR-23b-3p
  • MICRORNA.ORG:mmu-miR-23b-3p
  • MIRDB:mmu-miR-23b-3p
  • RNA22-MMU:mmu-miR-23b-3p
  • TARGETSCAN-VERT:mmu-miR-23b

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:12554860 "Numerous microRNPs in neuronal cells containing novel microRNAs" Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G RNA. 9:180-186(2003).
3. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
5. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
6. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).