Stem-loop mmu-mir-128-1

Accession

MI0000155

Symbol

MGI: Mir128-1

Description

Mus musculus mmu-mir-128-1 precursor miRNA

Gene family

MIPF0000048; mir-128

Literature search

77 open access papers mention mmu-mir-128-1
(569 sentences)

Sequence

646066 reads, 1663 reads per million, 105 experiments

guuggauuCGGGGCCGUAGCACUGUCUGAgagguuuacauuucUCACAGUGAACCGGUCUCUUUuucagc
((((((...(((((((...((((((..(((((((....)))))))))))))...)))))))...))))))

Structure

      uuC       UAG      CU       u 
guugga   GGGGCCG   CACUGU  GAgaggu u
||||||   |||||||   ||||||  |||||||  
cgacuu   CUCUGGC   GUGACA  CUcuuua a
      UUU       CAA      --       c 

Annotation confidence High

Comments

The most commonly cloned mature sequences derived from the previously annotated mir-128a and mir-128b were shown by Landgraf et al to be identical [3]. The sequences are therefore renamed mir-128-1 and mir-128-2.

Genome context

chr1: 128202361-128202430 [+]

Mature mmu-miR-128-1-5p

• Accession: MIMAT0016982
• Description: Mus musculus mmu-miR-128-1-5p mature miRNA
• Sequence: 9 - CGGGGCCGUAGCACUGUCUGA - 29
• Evidence: experimental ; Illumina [5]

Mature mmu-miR-128-3p

• Accession: MIMAT0000140
• Description: Mus musculus mmu-miR-128-3p mature miRNA
• Sequence: 44 - UCACAGUGAACCGGUCUCUUU - 64
• Evidence: experimental ; cloned [3], Illumina [4-5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739


3. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


4. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


5. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009