Stem-loop sequence mmu-mir-140

Accession

MI0000165 (change log)

Symbol

MGI:Mir140

Description

Mus musculus miR-140 stem-loop

Gene family

MIPF0000085; mir-140

Literature search

88 open access papers mention mmu-mir-140
(902 sentences)

Stem-loop

       -  a             a       uu   uc 
5' ccug cc gugguuuuacccu ugguagg  acg  a
   |||| || ||||||||||||| |||||||  |||   
3' ggac gg caccaagauggga accaucu  ugu  u
       a  -             c       --   cg 

Deep sequencing

7828962 reads, 1.68e+04 reads per million, 107 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr8: 107551244-107551313 [+]
• Overlapping transcripts:

  sense

  ENSMUST00000166615 ; Wwp2-201; intron 16

Database links

• EntrezGene:Mir140
• MGI:Mir140
• RNAcentral:URS000075E179_10090
• miRBase Tracker:MI0000165

Mature sequence mmu-miR-140-5p

• Accession: MIMAT0000151
• Previous IDs: mmu-miR-140
• Sequence: 6 - cagugguuuuacccuaugguag - 27
• Deep sequencing: 93421 reads, 106 experiments
• Evidence: experimental; cloned [1-4], Illumina [5-6]
• Database links:
  • RNAcentral:URS000026261D_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-140-5p
  • miRDB:mmu-miR-140-5p
  • microrna.org:mmu-miR-140-5p

Mature sequence mmu-miR-140-3p

• Accession: MIMAT0000152
• Previous IDs: mmu-miR-140*
• Sequence: 45 - uaccacaggguagaaccacgg - 65
• Deep sequencing: 7735244 reads, 107 experiments
• Evidence: experimental; cloned [2,4], Illumina [5-6]
• Database links:
  • RNAcentral:URS00000821E0_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-140-3p.2
  • miRDB:mmu-miR-140-3p
  • microrna.org:mmu-miR-140-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
3. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
5. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
6. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).