Stem-loop mmu-mir-145a

Accession

MI0000169

Symbol

MGI: Mir145a

Description

Mus musculus mmu-mir-145a precursor miRNA mir-145

Gene
family

RF00675; mir-145

Literature search

217 open access papers mention mmu-mir-145a
(1869 sentences)

Sequence

98920 reads, 774 reads per million, 89 experiments

cucacgGUCCAGUUUUCCCAGGAAUCCCUuggaugcuaagauggggAUUCCUGGAAAUACUGUUCUUGag
((((.((..((((.((.((((((((((((.............)))))))))))).)).))))..))))))

Structure

    c  UC    U  C            uggau 
cuca gG  CAGU UU CCAGGAAUCCCU     g
|||| ||  |||| || ||||||||||||     c
gaGU UC  GUCA AA GGUCCUUAgggg     u
    -  UU    U  A            uagaa 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr18: 61647825-61647894 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-145a

Mature mmu-miR-145a-5p

• Accession: MIMAT0000157
• Description: Mus musculus mmu-miR-145a-5p mature miRNA
• Sequence: 7 - GUCCAGUUUUCCCAGGAAUCCCU - 29
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

Mature mmu-miR-145a-3p

• Accession: MIMAT0004534
• Description: Mus musculus mmu-miR-145a-3p mature miRNA
• Sequence: 47 - AUUCCUGGAAAUACUGUUCUUG - 68
• Evidence: experimental ; cloned [2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009