Stem-loop sequence hsa-mir-204

Accession

MI0000284 (change log)

Symbol

HGNC:MIR204

Description

Homo sapiens miR-204 stem-loop

Gene family

MIPF0000042; mir-204

Literature search

191 open access papers mention hsa-mir-204
(1563 sentences)

Stem-loop

   ggcuacagucuuucu   -  -    ucg     u          a     u    gagaau 
5'                uca ug ugac   uggac ucccuuuguc uccua gccu      a
                  ||| || ||||   ||||| |||||||||| ||||| ||||      u
3'                ggu ac acug   acuug agggaaacgg agggu cgga      a
   --------------c   c  u    uua     c          a     -    ggaagu 

Deep sequencing

87215 reads, 400 reads per million, 146 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences [1]. Expression of the excised miR has been validated in zebrafish, and the ends mapped by cloning. Landgraf et al. confirm expression in human [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr9: 70809975-70810084 [-]
• Overlapping transcripts:

  intergenic

Database links

• EntrezGene:MIR204
• HGNC:MIR204
• RNAcentral:URS000039AE8A_9606
• miRBase Tracker:MI0000284

Mature sequence hsa-miR-204-5p

• Accession: MIMAT0000265
• Previous IDs: hsa-miR-204
• Sequence: 33 - uucccuuugucauccuaugccu - 54
• Deep sequencing: 84706 reads, 143 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS000029D9F1_9606
• Predicted targets:
  • TargetMiner:hsa-miR-204-5p
  • TargetScanVert:hsa-miR-204-5p
  • miRDB:hsa-miR-204-5p
  • microrna.org:hsa-miR-204-5p

Mature sequence hsa-miR-204-3p

• Accession: MIMAT0022693
• Sequence: 72 - gcugggaaggcaaagggacgu - 92
• Deep sequencing: 2289 reads, 92 experiments
• Evidence: not experimental
• Database links:
  • RNAcentral:URS000059A01D_9606
• Predicted targets:
  • TargetMiner:hsa-miR-204-3p
  • TargetScanVert:hsa-miR-204-3p
  • miRDB:hsa-miR-204-3p

References

1. PMID:12624257 "Vertebrate microRNA genes" Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP Science. 299:1540(2003).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).