Accession
MI0000371
Description
Drosophila melanogaster
dme-mir-34 precursor miRNA mir-34
Gene
family?
family?
RF00456;
mir-34
Literature search
35 open access papers mention dme-mir-34
(375 sentences)
(375 sentences)
Sequence
3285510
reads,
32190
reads per million, 49 experiments
aauuggcuaugcgcuuUGGCAGUGUGGUUAGCUGGUUGUGuagccaauuauugccguugacaauucaCAGCCACUAUCUUCACUGCCGCCgcgacaagc
.....(((.(((((..((((((((.((.(((.((((((((..(.((((.......)))).)....))))))))))).)).))))))))..))).)))))
.....(((.(((((..((((((((.((.(((.((((((((..(.((((.......)))).)....))))))))))).)).))))))))..))).)))))
Structure
aauug a - uu U U C --ua c ua
gcu ug cgc UGGCAGUG GG UAG UGGUUGUG g caau u
||| || ||| |||||||| || ||| |||||||| | |||| u
cga ac gcg GCCGUCAC UC AUC ACCGACac c guug g
----- - a CC U U - uuaa a cc
Annotation confidence
Medium
Do you think this miRNA is real?
Comments
This sequence is computationally predicted based on conservation in D. pseudoobscura and C. elegans. The precise 5' or 3' ends are unknown. Expression in D. melanogaster was confirmed by Northern blot analysis [1]. Aravin et al. later identify the 5' and 3' ends by cloning [3].
Genome context
chr3R: 10100936-10101034 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from dme-mir-34
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Database links
Mature dme-miR-34-5p
| Accession | MIMAT0000350 |
| Description | Drosophila melanogaster dme-miR-34-5p mature miRNA |
| Sequence | 17 - UGGCAGUGUGGUUAGCUGGUUGUG - 40 |
| Evidence |
experimental
Northern [1], cloned [3], 454 [4-5], Illumina [5] |
| Database links |
|
| Predicted targets |
|
Mature dme-miR-34-3p
| Accession | MIMAT0020812 |
| Description | Drosophila melanogaster dme-miR-34-3p mature miRNA |
| Sequence | 68 - CAGCCACUAUCUUCACUGCCGCC - 90 |
| Evidence | not_experimental |
| Database links |
|
References
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