Stem-loop mmu-mir-106b

Accession

MI0000407

Symbol

MGI: Mir106b

Description

Mus musculus mmu-mir-106b precursor miRNA mir-17

Gene
family

RF00051; mir-17

Literature search

113 open access papers mention mmu-mir-106b
(761 sentences)

Sequence

358667 reads, 2480 reads per million, 107 experiments

ccugcugggacUAAAGUGCUGACAGUGCAGAUagugguccucucugugcuaCCGCACUGUGGGUACUUGCUGCuccagcagg
(((((((((.(..(((((((.(((((((.....(((((.(.....).))))).))))))).)))))))...).)))))))))

Structure

         a -UA       G       AGAUa     c u 
ccugcuggg c   AAGUGCU ACAGUGC     guggu c c
||||||||| |   ||||||| |||||||     ||||| | u
ggacgaccu G   UUCAUGG UGUCACG     Caucg g c
         C UCG       G       ----C     u u 

Annotation confidence High

Comments

Reference [1] reported the same miRNA sequence with two different identifiers - miR-106b and miR-94.

Genome context

chr5: 138165737-138165818 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mmu-mir-106b

Mature mmu-miR-106b-5p

• Accession: MIMAT0000386
• Description: Mus musculus mmu-miR-106b-5p mature miRNA
• Sequence: 12 - UAAAGUGCUGACAGUGCAGAU - 32
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

Mature mmu-miR-106b-3p

• Accession: MIMAT0004582
• Description: Mus musculus mmu-miR-106b-3p mature miRNA
• Sequence: 52 - CCGCACUGUGGGUACUUGCUGC - 73
• Evidence: experimental ; cloned [2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12919684
   Embryonic stem cell-specific MicroRNAs
   "Houbaviy HB, Murray MF, Sharp PA"
   "Dev Cell (2003) 5:351-358


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009