Stem-loop sequence mmu-mir-130b

Accession

MI0000408 (change log)

Symbol

MGI:Mir130b

Description

Mus musculus miR-130b stem-loop

Gene family

MIPF0000034; mir-130

Literature search

82 open access papers mention mmu-mir-130b
(312 sentences)

Stem-loop

         u    ca       cc         a  guggg  u 
5' ggcuug ugga  cucuuuc  uguugcacu cu     cc c
   |||||| ||||  |||||||  ||||||||| ||     ||  
3' ccgggc gucu  gggaaag  guaacguga ga     gg u
         u    ac       ua         c  ----a  g 

Deep sequencing

99508 reads, 272 reads per million, 106 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr16: 17124061-17124142 [-]
• Overlapping transcripts:

  sense

  ENSMUST00000093336 ; 2610318N02Rik-201; intron 1

Clustered miRNAs

< 10kb from mmu-mir-130b

• mmu-mir-301b: chr16: 17124400-17124496 [-]
• mmu-mir-130b: chr16: 17124061-17124142 [-]

Database links

• EntrezGene:Mir130b
• MGI:Mir130b
• RNAcentral:URS000075D650_10090
• miRBase Tracker:MI0000408

Mature sequence mmu-miR-130b-5p

• Accession: MIMAT0004583
• Previous IDs: mmu-miR-130b*
• Sequence: 13 - acucuuucccuguugcacuacu - 34
• Deep sequencing: 8527 reads, 95 experiments
• Evidence: experimental; cloned [3], Illumina [4-5]
• Database links:
  • RNAcentral:URS00003BD810_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-130b-5p
  • miRDB:mmu-miR-130b-5p
  • microrna.org:mmu-miR-130b-5p

Mature sequence mmu-miR-130b-3p

• Accession: MIMAT0000387
• Previous IDs: mmu-miR-130b
• Sequence: 51 - cagugcaaugaugaaagggcau - 72
• Deep sequencing: 90954 reads, 106 experiments
• Evidence: experimental; cloned [1-3], Northern [1], Illumina [4-5]
• Database links:
  • RNAcentral:URS00002C0FCB_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-130b-3p
  • miRDB:mmu-miR-130b-3p
  • microrna.org:mmu-miR-130b-3p

References

1. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
2. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).