Stem-loop sequence mmu-mir-22

Accession

MI0000570 (change log)

Symbol

MGI:Mir22

Description

Mus musculus miR-22 stem-loop

Gene family

MIPF0000053; mir-22

Literature search

120 open access papers mention mmu-mir-22
(899 sentences)

Stem-loop

   a  --u   u   cc               -     a      u  ccu 
5'  cc   ggc gag  gcaguaguucuucag uggca gcuuua gu   g
    ||   ||| |||  ||||||||||||||| ||||| |||||| ||   a
3'  gg   ccg cuc  cguugucaagaaguu accgu cgaaau cg   c
   c  ucc   u   -c               g     -      -  acc 

Deep sequencing

3015381 reads, 1.16e+04 reads per million, 108 experiments

Confidence

Annotation confidence: high

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Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr11: 75463716-75463810 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000013983 ; Mir22hg-001; exon 2

  OTTMUST00000013984 ; Mir22hg-002; exon 2

  OTTMUST00000073516 ; Tlcd2-004; exon 2

  ENSMUST00000149940 ; Mir22hg-001; exon 2

  ENSMUST00000134345 ; Mir22hg-002; exon 2

  ENSMUST00000124718 ; Tlcd2-004; exon 2

Database links

• EntrezGene:Mirn22
• MGI:Mir22
• RNAcentral:URS000075DE23_10090
• miRBase Tracker:MI0000570

Mature sequence mmu-miR-22-5p

• Accession: MIMAT0004629
• Previous IDs: mmu-miR-22*
• Sequence: 19 - aguucuucaguggcaagcuuua - 40
• Deep sequencing: 17097 reads, 106 experiments
• Evidence: experimental; cloned [5], Illumina [6-7]
• Database links:
  • RNAcentral:URS0000142DC3_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-22-5p
  • miRDB:mmu-miR-22-5p
  • microrna.org:mmu-miR-22-5p

Mature sequence mmu-miR-22-3p

• Accession: MIMAT0000531
• Previous IDs: mmu-miR-22
• Sequence: 57 - aagcugccaguugaagaacugu - 78
• Deep sequencing: 2998275 reads, 108 experiments
• Evidence: experimental; cloned [1-2,4-5], Northern [2], Illumina [6]
• Database links:
  • RNAcentral:URS0000096022_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-22-3p
  • miRDB:mmu-miR-22-3p
  • microrna.org:mmu-miR-22-3p

References

1. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
2. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
3. PMID:12554860 "Numerous microRNPs in neuronal cells containing novel microRNAs" Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G RNA. 9:180-186(2003).
4. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
5. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
6. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
7. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).