Stem-loop sequence mmu-mir-27a

Accession

MI0000578 (change log)

Symbol

MGI:Mir27a

Description

Mus musculus miR-27a stem-loop

Gene family

MIPF0000036; mir-27

Literature search

164 open access papers mention mmu-mir-27a
(1476 sentences)

Stem-loop

   u  -  u a  a  a         ug  u       a  uccac 
5'  gg cc g gg gc gggcuuagc  cu gugagca gg     a
    || || | || || |||||||||  || ||||||| ||      
3'  cc gg c cc cg cuugaaucg  ga cacuugu cu     g
   c  a  u -  c  c         gu  -       g  gaaac 

Deep sequencing

2305954 reads, 6.61e+03 reads per million, 107 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr8: 84208672-84208758 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-27a

• mmu-mir-23a: chr8: 84208518-84208592 [+]
• mmu-mir-27a: chr8: 84208672-84208758 [+]
• mmu-mir-24-2: chr8: 84208815-84208921 [+]
• mmu-mir-3074-2: chr8: 84208825-84208907 [-]

Database links

• EntrezGene:Mirn27a
• MGI:Mir27a
• RNAcentral:URS000075AEFF_10090
• miRBase Tracker:MI0000578

Mature sequence mmu-miR-27a-5p

• Accession: MIMAT0004633
• Previous IDs: mmu-miR-27a*
• Sequence: 14 - agggcuuagcugcuugugagca - 35
• Deep sequencing: 7835 reads, 104 experiments
• Evidence: experimental; cloned [5], Illumina [6-7]
• Database links:
  • RNAcentral:URS00001B341F_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-27a-5p
  • miRDB:mmu-miR-27a-5p
  • microrna.org:mmu-miR-27a-5p

Mature sequence mmu-miR-27a-3p

• Accession: MIMAT0000537
• Previous IDs: mmu-miR-27a
• Sequence: 56 - uucacaguggcuaaguuccgc - 76
• Deep sequencing: 2297953 reads, 107 experiments
• Evidence: experimental; cloned [1-2,4-5], Northern [1], Illumina [6]
• Database links:
  • RNAcentral:URS00003B95DA_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-27a-3p
  • miRDB:mmu-miR-27a-3p
  • microrna.org:mmu-miR-27a-3p

References

1. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
2. PMID:12007417 "Identification of tissue-specific microRNAs from mouse" Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T Curr Biol. 12:735-739(2002).
3. PMID:12554860 "Numerous microRNPs in neuronal cells containing novel microRNAs" Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G RNA. 9:180-186(2003).
4. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
5. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
6. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
7. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).