Stem-loop rno-mir-350-1

Accession

MI0000639

Description

Rattus norvegicus rno-mir-350-1 precursor miRNA

Literature search

3 open access papers mention rno-mir-350-1
(7 sentences)

Sequence

17940 reads, 18.0 reads per million, 479 experiments

agaugccuugcuccuacaagaguAAAGUGCACGUGCUUUGGGACagugaggaaaauaaugUUCACAAAGCCCAUACACUUUCacccuuuaggagaguug
..........((((((.(((.((((((((.....(((((((((((.............))))).)))))).....)))))).)).))))))))).....

Structure

agaugccuug      c   a  -      CACGU      -     gugag 
          cuccua aag gu AAAGUG     GCUUUG GGACa     g
          |||||| ||| || ||||||     |||||| |||||     a
          gaggau uuc ca UUUCAC     CGAAAC CUUgu     a
-----guuga      -   c  C      AUACC      A     aauaa 

Annotation confidence High

Comments

Kim et al. cloned 40 new miRNAs from rat E18 primary cortical neurons [1]. This rat miRNA has a predicted homologue in mouse (MIR:MI0000640). The sequence reported in [1] contains a 5' terminal A residue, which conflicts with the precursor sequence shown here.

Genome context

chr13: 43827492-43827590 [+]

Mature rno-miR-350-5p

• Accession: MIMAT0061419
• Description: Rattus norvegicus rno-miR-350-5p mature miRNA
• Sequence: 24 - AAAGUGCACGUGCUUUGGGAC - 44
• Evidence: experimental ; cloned [1], SOLiD [2]

Mature rno-miR-350-3p

• Accession: MIMAT0000604
• Description: Rattus norvegicus rno-miR-350-3p mature miRNA
• Sequence: 61 - UUCACAAAGCCCAUACACUUUC - 82
• Evidence: experimental ; cloned [1], SOLiD [2]

References

1. PubMed ID: 14691248
   Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
   "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
   "Proc Natl Acad Sci U S A (2004) 101:360-365


2. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249