Stem-loop sequence mmu-mir-19a

Accession

MI0000688 (change log)

Symbol

MGI:Mir19a

Description

Mus musculus miR-19a stem-loop

Gene family

MIPF0000011; mir-19

Literature search

140 open access papers mention mmu-mir-19a
(762 sentences)

Stem-loop

       c  u                 --      ---    ag 
5' gcag cc cuguuaguuuugcauag  uugcac   uaca  a
   |||| || |||||||||||||||||  ||||||   ||||  a
3' cguc gg gguagucaaaacguauc  aacgug   augu  g
       c  u                 ua      uug    aa 

Deep sequencing

317097 reads, 2.5e+03 reads per million, 107 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr14: 115044000-115044081 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000083388 ; Mir17hg-001; exon 2

  ENSMUST00000134140 ; Mir17hg-001; exon 2

Clustered miRNAs

< 10kb from mmu-mir-19a

• mmu-mir-17: chr14: 115043671-115043754 [+]
• mmu-mir-18a: chr14: 115043851-115043946 [+]
• mmu-mir-19a: chr14: 115044000-115044081 [+]
• mmu-mir-20a: chr14: 115044157-115044263 [+]
• mmu-mir-19b-1: chr14: 115044305-115044391 [+]
• mmu-mir-92a-1: chr14: 115044427-115044506 [+]

Database links

• EntrezGene:Mirn19a
• MGI:Mir19a
• RNAcentral:URS000075E79E_10090
• miRBase Tracker:MI0000688

Mature sequence mmu-miR-19a-5p

• Accession: MIMAT0004660
• Previous IDs: mmu-miR-19a*
• Sequence: 13 - uaguuuugcauaguugcacuac - 34
• Deep sequencing: 748 reads, 58 experiments
• Evidence: experimental; cloned [2], Illumina [3-4]
• Database links:
  • RNAcentral:URS000006AA40_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-19a-5p
  • miRDB:mmu-miR-19a-5p
  • microrna.org:mmu-miR-19a-5p

Mature sequence mmu-miR-19a-3p

• Accession: MIMAT0000651
• Previous IDs: mmu-miR-19a
• Sequence: 49 - ugugcaaaucuaugcaaaacuga - 71
• Deep sequencing: 316334 reads, 107 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS000006FDD4_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-19a-3p
  • miRDB:mmu-miR-19a-3p
  • microrna.org:mmu-miR-19a-3p

References

1. PMID:12554860 "Numerous microRNPs in neuronal cells containing novel microRNAs" Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G RNA. 9:180-186(2003).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).