Stem-loop sequence hsa-mir-377

Accession

MI0000785 (change log)

Symbol

HGNC:MIR377

Description

Homo sapiens miR-377 stem-loop

Gene family

MIPF0000018; mir-154

Literature search

65 open access papers mention hsa-mir-377
(518 sentences)

Stem-loop

   uu              c   -    a    - uuu 
5'   gagcagagguugcc uug guga uucg c   a
     |||||||||||||| ||| |||| |||| |   u
3'   uuuguuuucaacgg aac cacu aagu g   u
   -g              a   a    -    u uau 

Deep sequencing

5640 reads, 15.3 reads per million, 124 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr14: 101062050-101062118 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from hsa-mir-377

• hsa-mir-487a: chr14: 101052446-101052525 [+]
• hsa-mir-382: chr14: 101054306-101054381 [+]
• hsa-mir-134: chr14: 101054687-101054759 [+]
• hsa-mir-668: chr14: 101055258-101055323 [+]
• hsa-mir-485: chr14: 101055419-101055491 [+]
• hsa-mir-323b: chr14: 101056219-101056300 [+]
• hsa-mir-154: chr14: 101059755-101059838 [+]
• hsa-mir-496: chr14: 101060573-101060674 [+]
• hsa-mir-377: chr14: 101062050-101062118 [+]
• hsa-mir-541: chr14: 101064495-101064578 [+]
• hsa-mir-409: chr14: 101065300-101065378 [+]
• hsa-mir-412: chr14: 101065447-101065537 [+]
• hsa-mir-369: chr14: 101065598-101065667 [+]
• hsa-mir-410: chr14: 101065912-101065991 [+]
• hsa-mir-656: chr14: 101066724-101066801 [+]

Database links

• EntrezGene:MIR377
• HGNC:MIR377
• RNAcentral:URS000075AF10_9606
• miRBase Tracker:MI0000785

Mature sequence hsa-miR-377-5p

• Accession: MIMAT0004689
• Previous IDs: hsa-miR-377*
• Sequence: 7 - agagguugcccuuggugaauuc - 28
• Deep sequencing: 1215 reads, 101 experiments
• Evidence: experimental; cloned [3]
• Database links:
  • RNAcentral:URS000036BEF1_9606
• Predicted targets:
  • TargetMiner:hsa-miR-377-5p
  • TargetScanVert:hsa-miR-377-5p
  • miRDB:hsa-miR-377-5p
  • microrna.org:hsa-miR-377-5p

Mature sequence hsa-miR-377-3p

• Accession: MIMAT0000730
• Previous IDs: hsa-miR-377
• Sequence: 45 - aucacacaaaggcaacuuuugu - 66
• Deep sequencing: 4424 reads, 124 experiments
• Evidence: experimental; cloned [1-3]
• Database links:
  • RNAcentral:URS000007F792_9606
• Predicted targets:
  • TargetMiner:hsa-miR-377-3p
  • TargetScanVert:hsa-miR-377-3p
  • miRDB:hsa-miR-377-3p
  • microrna.org:hsa-miR-377-3p

References

1. PMID:15891114 "Clustering and conservation patterns of human microRNAs" Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H Nucleic Acids Res. 33:2697-2706(2005).
2. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).