Stem-loop sequence mmu-mir-379

Accession

MI0000796

Symbol

MGI:Mir379

Description

Mus musculus miR-379 stem-loop

Gene family

MIPF0000126; mir-379

Stem-loop

    a    a       ga       -  uua 
agag uggu gacuaug  acguagg cg   u
|||| |||| |||||||  ||||||| ||   g
ucuc auca cugguac  uguaucc gu   u
    a    c       aa       a  uuu 

Deep sequencing

230315 reads, 75 experiments

Genome context

• Coordinates (GRCm38): chr12: 109709060-109709125 [+]
• Overlapping transcripts:

  sense

  ENSMUST00000083564 ; Mir379-201; exon 1

Clustered miRNAs

< 10kb from mmu-mir-379

• mmu-mir-379: chr12: 109709060-109709125 [+]
• mmu-mir-411: chr12: 109710175-109710256 [+]
• mmu-mir-299a: chr12: 109710638-109710700 [+]
• mmu-mir-299b: chr12: 109710645-109710693 [-]
• mmu-mir-380: chr12: 109711803-109711863 [+]
• mmu-mir-1197: chr12: 109712317-109712436 [+]
• mmu-mir-323: chr12: 109712508-109712593 [+]
• mmu-mir-758: chr12: 109712810-109712890 [+]
• mmu-mir-329: chr12: 109713481-109713577 [+]
• mmu-mir-494: chr12: 109715318-109715402 [+]
• mmu-mir-679: chr12: 109715577-109715650 [+]
• mmu-mir-1193: chr12: 109715671-109715791 [+]
• mmu-mir-666: chr12: 109717085-109717183 [+]
• mmu-mir-543: chr12: 109717258-109717333 [+]
• mmu-mir-495: chr12: 109718754-109718816 [+]

Database links

• ENTREZGENE: 723858;Mir379
• MGI: 3619386;Mir379

Mature sequence mmu-miR-379-5p

• Accession: MIMAT0000743
• Previous IDs: mmu-miR-379
• Sequence: 6 - ugguagacuauggaacguagg - 26
• Deep sequencing: 148557 reads, 67 experiments
• Evidence: experimental; cloned [1-4], Solexa [5,7]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-379-5p
  • MICRORNA.ORG:mmu-miR-379-5p
  • MIRDB:mmu-miR-379-5p
  • RNA22-MMU:mmu-miR-379-5p
  • TARGETSCAN-VERT:mmu-miR-379

Mature sequence mmu-miR-379-3p

• Accession: MIMAT0017080
• Previous IDs: mmu-miR-379*
• Sequence: 43 - uauguaacaugguccacuaacu - 64
• Deep sequencing: 81674 reads, 57 experiments
• Evidence: experimental; 454 [6], Solexa [7]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-379-3p
  • MIRDB:mmu-miR-379-3p
  • RNA22-MMU:mmu-miR-379-3p

References

1. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
2. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
3. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
4. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
5. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
6. PMID:20668074 "Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68" Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H J Virol. 84:10266-10275(2010).
7. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).