Stem-loop mmu-mir-381

Accession

MI0000798

Symbol

MGI: Mir381

Description

Mus musculus mmu-mir-381 precursor miRNA

Literature search

31 open access papers mention mmu-mir-381
(249 sentences)

Sequence

211186 reads, 1413 reads per million, 81 experiments

uacuuaaAGCGAGGUUGCCCUUUGUAUAUUcgguuuauugacauggaaUAUACAAGGGCAAGCUCUCUGUgagua
((((((.((.(((.((((((((.((((((((.((........)).)))))))))))))))).))).)).))))))

Structure

      a  C   G        U        g  uua 
uacuua AG GAG UUGCCCUU GUAUAUUc gu   u
|||||| || ||| |||||||| |||||||| ||    
augagU UC CUC AACGGGAA CAUAUaag ua   u
      G  U   G        -        g  cag 

Annotation confidence High

Genome context

chr12: 109726822-109726896 [+]

Clustered miRNAs

17 other miRNAs are < 10 kb from mmu-mir-381

Mature mmu-miR-381-5p

• Accession: MIMAT0017081
• Description: Mus musculus mmu-miR-381-5p mature miRNA
• Sequence: 8 - AGCGAGGUUGCCCUUUGUAUAUU - 30
• Evidence: experimental ; Illumina [4]

Mature mmu-miR-381-3p

• Accession: MIMAT0000746
• Description: Mus musculus mmu-miR-381-3p mature miRNA
• Sequence: 49 - UAUACAAGGGCAAGCUCUCUGU - 70
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009