Stem-loop sequence rno-mir-19b-1

Accession

MI0000847 (change log)

Description

Rattus norvegicus miR-19b-1 stem-loop

Gene family

MIPF0000011; mir-19

Literature search

45 open access papers mention rno-mir-19b-1
(168 sentences)

Stem-loop

       ggu                 -  -      uc    uguau 
5' cacu   cuaugguuaguuuugca gg uuugca  cagc     a
   ||||   ||||||||||||||||| || ||||||  ||||     a
3' gugg   ggugucagucaaaacgu cc aaacgu  gucg     u
       --u                 a  u      --    ucuua 

Deep sequencing

155597 reads, 153 reads per million, 499 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (Rnor_6.0; GCA_000001895.4): chr15: 100180464-100180550 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from rno-mir-19b-1

• rno-mir-17-1: chr15: 100179879-100179962 [+]
• rno-mir-18a: chr15: 100180015-100180110 [+]
• rno-mir-19a: chr15: 100180162-100180243 [+]
• rno-mir-20a: chr15: 100180334-100180418 [+]
• rno-mir-19b-1: chr15: 100180464-100180550 [+]
• rno-mir-92a-1: chr15: 100180586-100180663 [+]

Database links

• EntrezGene:Mir19b-1
• miRBase Tracker:MI0000847

Mature sequence rno-miR-19b-1-5p

• Accession: MIMAT0017096
• Previous IDs: rno-miR-19b-1*
• Sequence: 16 - aguuuugcagguuugcauccag - 37
• Deep sequencing: 131 reads, 93 experiments
• Evidence: experimental; SOLiD [4]
• Predicted targets:
  • TargetScanVert:rno-miR-19b-1-5p
  • miRDB:rno-miR-19b-1-5p

Mature sequence rno-miR-19b-3p

• Accession: MIMAT0000788
• Previous IDs: rno-miR-19b
• Sequence: 54 - ugugcaaauccaugcaaaacuga - 76
• Deep sequencing: 310991 reads, 499 experiments
• Evidence: experimental; cloned [1-3], SOLiD [4]
• Predicted targets:
  • TargetScanVert:rno-miR-19b-3p
  • miRDB:rno-miR-19b-3p
  • microrna.org:rno-miR-19b-3p

References

1. PMID:14691248 "Identification of many microRNAs that copurify with polyribosomes in mammalian neurons" Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G Proc Natl Acad Sci U S A. 101:360-365(2004).
2. PMID:16766679 "Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes" Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H Genes Dev. 20:1732-1743(2006).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20403161 "Small RNA expression and strain specificity in the rat" Linsen SE, de Wit E, de Bruijn E, Cuppen E BMC Genomics. 11:249(2010).