Stem-loop rno-mir-24-1

Accession

MI0000854

Description

Rattus norvegicus rno-mir-24-1 precursor miRNA

Gene family

MIPF0000041; mir-24

Literature search

41 open access papers mention rno-mir-24-1
(196 sentences)

Sequence

258575 reads, 268 reads per million, 493 experiments

cuccgGUGCCUACUGAGCUGAUAUCAGuucucauuucacacacUGGCUCAGUUCAGCAGGAACAGgag
((((.((.(((.(((((((((..(((((.............))))).))))))))).))).)).))))

Structure

    g  G   A         UA     ucuca 
cucc GU CCU CUGAGCUGA  UCAGu     u
|||| || ||| |||||||||  |||||     u
gagG CA GGA GACUUGACU  GGUca     u
    A  A   C         -C     cacac 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chr17: 823968-824035 [+]

Clustered miRNAs

3 other miRNAs are < 10 kb from rno-mir-24-1

Mature rno-miR-24-1-5p

• Accession: MIMAT0003153
• Description: Rattus norvegicus rno-miR-24-1-5p mature miRNA
• Sequence: 6 - GUGCCUACUGAGCUGAUAUCAG - 27
• Evidence: experimental ; cloned [2-3], Northern [2], SOLiD [5]

Mature rno-miR-24-3p

• Accession: MIMAT0000794
• Description: Rattus norvegicus rno-miR-24-3p mature miRNA
• Sequence: 44 - UGGCUCAGUUCAGCAGGAACAG - 65
• Evidence: experimental ; cloned [1-4], Northern [2], SOLiD [5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249


4. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68


5. PubMed ID: 17805466
   Cloning and identification of novel microRNAs from rat hippocampus
   "He X, Zhang Q, Liu Y, Pan X"
   "Acta Biochim Biophys Sin (Shanghai) (2007) 39:708-714