miRBase entry: gga-mir-199-2

Stem-loop gga-mir-199-2


Accession
MI0001220
Description
Gallus gallus gga-mir-199-2 precursor miRNA
Gene family
MIPF0000040; mir-199

Literature search
8 open access papers mention gga-mir-199-2
(25 sentences)

Sequence

83325 reads, 1409 reads per million, 5 experiments
gaagcguccggagauccugcuccgucgcCCCAGUGUUCAGACUACCUGUUCaggacaaugcuguugUACAGUAGUCUGCACAUUGGuuagacugggcaagggaaagca
...((.(((((....))(((((.(((...(((((((.((((((((.(((....((((....))))..))))))))))).)))))))...))).)))))..)))..)).

Structure
gaa  -g   ggagaucc     c   gcC       U        C   UCag    a 
   gc  ucc        ugcuc guc   CCAGUGU CAGACUAC UGU    gaca u
   ||  |||        ||||| |||   ||||||| |||||||| |||    ||||  
   cg  agg        acggg cag   GGUUACA GUCUGAUG ACA    uugu g
--a  aa   ------ga     u   auu       C        -   --Ug    c 


Annotation confidence Not enough data
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Comments
Chicken has two loci predicted to express miR-199. mir-199-2 (MIR:MI0001220) is homologous to mir-199a-2 in human (MIR:MI0000281) and mouse (MIR:MI0000713). mir-199-1 (MIR:MI0001245) is homologous to mir-199b in human (MIR:MI0000282) and mouse (MIR:MI0000714). The expression of chicken miR-199 has been verified experimentally [2].

Genome context
chr8: 4652464-4652571 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from gga-mir-199-2
Name Accession Chromosome Start End Strand Confidence




Database links

Mature gga-miR-199-5p

Accession MIMAT0001152
Description Gallus gallus gga-miR-199-5p mature miRNA
Sequence 29 - CCCAGUGUUCAGACUACCUGUUC - 51
Evidence experimental
cloned [2], Northern [2]
Database links
Predicted targets

Mature gga-miR-199-3p

Accession MIMAT0003721
Description Gallus gallus gga-miR-199-3p mature miRNA
Sequence 67 - UACAGUAGUCUGCACAUUGG - 86
Evidence experimental
cloned [2], Northern [2]
Database links
Predicted targets

References

  1. PubMed ID: 15592404
    Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
    "International Chicken Genome Sequencing Consortium"
    "Nature (2004) 432:695-716


  2. "McBride D, Carre W, Law A, Clinton M"
    (None) None:

  3. PubMed ID: 16750530
    Identification of microRNAs from different tissues of chicken embryo and adult chicken
    "Xu H, Wang X, Du Z, Li N"
    "FEBS Lett (2006) 580:3610-3616