Stem-loop sequence dre-mir-203a

AccessionMI0001376 (change log)
Previous IDsdre-mir-203
DescriptionDanio rerio miR-203a stem-loop
Gene family MIPF0000108; mir-203
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled MiR-203. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

In molecular biology miR-203 is a short non-coding RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms, such as translational repression and Argonaute-catalyzed messenger RNA cleavage. miR-203 has been identified as a skin-specific microRNA, and it forms an expression gradient that defines the boundary between proliferative epidermal basal progenitors and terminally differentiating suprabasal cells. It has also been found upregulated in psoriasis and differentially expressed in some types of cancer.

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   guguuugggucucuucuggucccu     gc         u    g    a     cua 
5'                         cuggu  agugguucu aaca uuca caguu   u
                           |||||  ||||||||| |||| |||| |||||   c
3'                         gacca  ucaccagga uugu aagu guuaa   u
   ------------------------     gu         u    a    -     aac 
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Genome context
Coordinates (GRCz11; GCA_000002035.4) Overlapping transcripts
chr17: 45808153-45808248 [+]
Database links

Mature sequence dre-miR-203a-5p

Accession MIMAT0031923

32 - 


 - 55

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Evidence not experimental
Database links

Mature sequence dre-miR-203a-3p

Accession MIMAT0001278
Previous IDsdre-miR-203a

70 - 


 - 91

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Evidence experimental; cloned [1-2]
Database links
Predicted targets


PMID:12624257 "Vertebrate microRNA genes" Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP Science. 299:1540(2003).
PMID:15937218 "The developmental miRNA profiles of zebrafish as determined by small RNA cloning" Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T Genes Dev. 19:1288-1293(2005).