miRBase entry: mmu-mir-448

Stem-loop mmu-mir-448


Accession
MI0001638
Symbol
MGI: Mir448
Description
Mus musculus mmu-mir-448 precursor miRNA
Gene family
MIPF0000149; mir-448

Literature search
8 open access papers mention mmu-mir-448
(17 sentences)

Sequence

2052 reads, 50 reads per million, 24 experiments
acgaggagguuGAACAUCCUGCAUAGUGCUGCCaggaaaucccuacuucauacuaagagggggcuggcuggUUGCAUAUGUAGGAUGUCCCAUcuccuggcccacuucguca
.(.(((((((.(.((((((((((((.(((.(((((....(((((.(((......)))))))).....))))).))))))))))))))).).))))))).)............

Structure
-----------a g       u A            G   U     -gaaa     a   ca 
            c aggaggu G ACAUCCUGCAUA UGC GCCag     ucccu cuu  u
            | ||||||| | |||||||||||| ||| |||||     ||||| |||   
            g uccucUA C UGUAGGAUGUAU ACG Ugguc     gggga gaa  a
acugcuucaccc g       C C            -   U     ggucg     -   uc 


Annotation confidence High
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Comments
Xie et al. [1] refer to this sequence by the internal identifier MIR64. The sequence is unrelated to C. elegans mir-64 (MIR:MI0000035).

Genome context
chrX: 147158210-147158321 [+]

Database links

Mature mmu-miR-448-5p

Accession MIMAT0017176
Description Mus musculus mmu-miR-448-5p mature miRNA
Sequence 12 - GAACAUCCUGCAUAGUGCUGCC - 33
Evidence experimental
Illumina [3]
Database links
Predicted targets

Mature mmu-miR-448-3p

Accession MIMAT0001533
Description Mus musculus mmu-miR-448-3p mature miRNA
Sequence 72 - UUGCAUAUGUAGGAUGUCCCAU - 93
Evidence experimental
Illumina [2-3]
Database links
Predicted targets

References

  1. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  2. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  3. PubMed ID: 15735639
    Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
    "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
    "Nature (2005) 434:338-345