miRBase entry: rno-mir-450a

Stem-loop rno-mir-450a


Accession
MI0001654
Description
Rattus norvegicus rno-mir-450a precursor miRNA
Gene family
MIPF0000128; mir-450

Literature search
4 open access papers mention rno-mir-450a
(15 sentences)

Sequence

413504 reads, 377 reads per million, 493 experiments
gagagaugcggagcuguUUUUGCGAUGUGUUCCUAAUGUgugcuacaauuaUAUUGGGAACAUUUUGCAUAAauaguuuuacaucgacaca
....((((.((((((((((.(((((.((((((((((((((.........)))))))))))))).))))).)))))))))).))))......

Structure
--gaga    c          U     U              ugc 
      gaug ggagcuguUU UGCGA GUGUUCCUAAUGUg   u
      |||| |||||||||| ||||| ||||||||||||||   a
      cuac uuuugauaAA ACGUU UACAAGGGUUAUau   c
acacag    a          U     U              uaa 


Annotation confidence High
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Comments
Xie et al. [1] refer to this sequence by the internal identifier MIR238. The sequence is unrelated to C. elegans mir-238 (MIR:MI0000313).

Genome context
chrX: 158153377-158153467 [+]
Clustered miRNAs
6 other miRNAs are < 10 kb from rno-mir-450a
Name Accession Chromosome Start End Strand Confidence




Database links

Mature rno-miR-450a-5p

Accession MIMAT0001547
Description Rattus norvegicus rno-miR-450a-5p mature miRNA
Sequence 18 - UUUUGCGAUGUGUUCCUAAUGU - 39
Evidence experimental
SOLiD [2]

Mature rno-miR-450a-3p

Accession MIMAT0017183
Description Rattus norvegicus rno-miR-450a-3p mature miRNA
Sequence 52 - UAUUGGGAACAUUUUGCAUAA - 72
Evidence experimental
SOLiD [2]

References

  1. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  2. PubMed ID: 15735639
    Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
    "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
    "Nature (2005) 434:338-345