Stem-loop sequence hsa-mir-431

Accession

MI0001721 (change log)

Symbol

HGNC:MIR431

Description

Homo sapiens miR-431 stem-loop

Gene family

MIPF0000142; mir-431

Literature search

28 open access papers mention hsa-mir-431
(46 sentences)

Stem-loop

   ---------------ucc  c     c       u          c  u a     ----   aca 
5'                   ug uuguc ugcgagg gucuugcagg cg c ugcag    gcc   c
                     || ||||| ||||||| |||||||||| || | |||||    |||    
3'                   ac agcag acgcucu cgggacguuc gc g acguu    ugg   u
   gcagcaaccacuacuccu  -     a       u          u  u g     gcaa   cag 

Deep sequencing

3155 reads, 0 reads per million, 93 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr14: 100881007-100881120 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000414309 ; WDR25-007; intron 1

  OTTHUMT00000414313 ; WDR25-008; intron 1

  OTTHUMT00000414315 ; WDR25-005; intron 1

  OTTHUMT00000414316 ; WDR25-006; intron 1

  OTTHUMT00000414310 ; WDR25-002; intron 2

  OTTHUMT00000414311 ; WDR25-001; intron 2

  OTTHUMT00000414312 ; WDR25-004; intron 2

  OTTHUMT00000414314 ; WDR25-003; intron 2

  ENST00000555775 ; WDR25-007; intron 1

  ENST00000554492 ; WDR25-008; intron 1

  ENST00000557710 ; WDR25-005; intron 1

  ENST00000542471 ; WDR25-006; intron 1

  ENST00000554998 ; WDR25-002; intron 2

  ENST00000402312 ; WDR25-001; intron 2

  ENST00000335290 ; WDR25-004; intron 2

  ENST00000554175 ; WDR25-003; intron 2

Clustered miRNAs

< 10kb from hsa-mir-431

• hsa-mir-337: chr14: 100874493-100874585 [+]
• hsa-mir-665: chr14: 100875033-100875104 [+]
• hsa-mir-431: chr14: 100881007-100881120 [+]
• hsa-mir-433: chr14: 100881886-100881978 [+]
• hsa-mir-127: chr14: 100882979-100883075 [+]
• hsa-mir-432: chr14: 100884483-100884576 [+]
• hsa-mir-136: chr14: 100884702-100884783 [+]

Database links

• EntrezGene:MIR431
• HGNC:MIR431
• RNAcentral:URS000067427D_9606
• miRBase Tracker:MI0001721

Mature sequence hsa-miR-431-5p

• Accession: MIMAT0001625
• Previous IDs: hsa-miR-431
• Sequence: 20 - ugucuugcaggccgucaugca - 40
• Deep sequencing: 224 reads, 59 experiments
• Evidence: experimental; cloned [1-2]
• Database links:
  • RNAcentral:URS000043908D_9606
• Predicted targets:
  • TargetMiner:hsa-miR-431-5p
  • TargetScanVert:hsa-miR-431-5p
  • miRDB:hsa-miR-431-5p
  • microrna.org:hsa-miR-431-5p

Mature sequence hsa-miR-431-3p

• Accession: MIMAT0004757
• Previous IDs: hsa-miR-431*
• Sequence: 63 - caggucgucuugcagggcuucu - 84
• Deep sequencing: 2880 reads, 76 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS0000086A4D_9606
• Predicted targets:
  • TargetMiner:hsa-miR-431-3p
  • TargetScanVert:hsa-miR-431-3p
  • miRDB:hsa-miR-431-3p
  • microrna.org:hsa-miR-431-3p

References

1. PMID:15891114 "Clustering and conservation patterns of human microRNAs" Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H Nucleic Acids Res. 33:2697-2706(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).