Stem-loop sequence dre-mir-10b-2

AccessionMI0001887
DescriptionDanio rerio miR-10b-2 stem-loop
Gene family MIPF0000033; mir-10
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-10_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The miR-10 microRNA precursor is a short non-coding RNA gene involved in gene regulation. It is part of an RNA gene family which contains miR-10, miR-51, miR-57, miR-99 and miR-100. miR-10, miR-99 and miR-100 have now been predicted or experimentally confirmed in a wide range of species. (MIPF0000033, MIPF0000025) mir-51 and mir-57 have currently only been identified in the nematode Caenorhabditis elegans (MIPF0000268, MIPF0000271). microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In this case the mature sequence comes from the 5' arm of the precursor. The mature products are thought to have regulatory roles through complementarity to mRNA.

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Stem-loop
   -gua         a   ac        ac  a       uccaaaa 
5'     gucgucuau ugu  ccuguaga  cg auuugug       c
       ||||||||| |||  ||||||||  || |||||||        
3'     cagcgggua aua  ggacaucu  gc uaaacgc       a
   aaug         c   -a        cu  a       uaaaacu 
Get sequence
Deep sequencing
26642 reads, 2.63e+03 reads per million, 4 experiments
Confidence Annotation confidence: high
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Genome context
Coordinates (Zv9) Overlapping transcripts
23: 36181545-36181636 [+]
sense
OTTDART00000059220 ; hoxc3a-004; intron 2
OTTDART00000019709 ; hoxc3a-003; intron 2
OTTDART00000019708 ; hoxc3a-002; intron 2
ENSDART00000154825 ; hoxc3a-004; intron 2
ENSDART00000128533 ; hoxc3a-003; intron 2
ENSDART00000137507 ; hoxc3a-002; intron 2
ENSDART00000082472 ; hoxc3a-201; intron 2
antisense
OTTDART00000058629 ; si:dkey-81p22.11-002; intron 3
OTTDART00000059834 ; si:dkey-81p22.11-004; intron 3
OTTDART00000059835 ; si:dkey-81p22.11-003; intron 4
OTTDART00000059838 ; si:dkey-81p22.11-007; intron 4
OTTDART00000019699 ; si:dkey-81p22.11-001; intron 5
OTTDART00000059833 ; si:dkey-81p22.11-008; intron 5
OTTDART00000059837 ; si:dkey-81p22.11-006; intron 5
OTTDART00000059836 ; si:dkey-81p22.11-005; intron 6
ENSDART00000153206 ; si:dkey-81p22.11-002; intron 3
ENSDART00000155040 ; si:dkey-81p22.11-004; intron 3
ENSDART00000156899 ; si:dkey-81p22.11-003; intron 4
ENSDART00000155063 ; si:dkey-81p22.11-007; intron 4
ENSDART00000143609 ; si:dkey-81p22.11-001; intron 5
ENSDART00000155822 ; si:dkey-81p22.11-008; intron 5
ENSDART00000153852 ; si:dkey-81p22.11-006; intron 5
ENSDART00000157077 ; si:dkey-81p22.11-005; intron 6
Database links

Mature sequence dre-miR-10b-5p

Accession MIMAT0001268
Previous IDsdre-miR-10b
Sequence

16 - 

uacccuguagaaccgaauuugug

 - 38

Get sequence
Deep sequencing29162 reads, 4 experiments
Evidence experimental; cloned [1]
Validated targets

Mature sequence dre-miR-10b-2-3p

Accession MIMAT0031934
Sequence

57 - 

caaauacgucucuacaggaau

 - 77

Get sequence
Deep sequencing213 reads, 3 experiments
Evidence not experimental

References

1
PMID:15937218 "The developmental miRNA profiles of zebrafish as determined by small RNA cloning" Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T Genes Dev. 19:1288-1293(2005).