Stem-loop sequence dre-mir-19c

AccessionMI0001905 (change log)
DescriptionDanio rerio miR-19c stem-loop
Gene family MIPF0000011; mir-19
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-19_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

There are 89 known sequences today in the microRNA 19 (miR-19) family but it will change quickly. They are found in a large number of vertebrate species. The miR-19 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. Within the human and mouse genome there are three copies of this microRNA that are processed from multiple predicted precursor hairpins: mouse: * miR-19a on chromosome 14 (MI0000688) * miR-19b-1 on chromosome 14 (MI0000718) * miR-19b-2 on chromosome X (MI0000546) human: * miR-19a on chromosome 13 (MI0000073) * miR-19b-1 on chromosome 13 (MI0000074) * miR-19b-2 on chromosome X (MI000075). MiR-19 has now been predicted or experimentally confirmed (MIPF0000011). In this case the mature sequence is excised from the 3' arm of the hairpin precursor.

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   u  aaaag     uuauc  g             -     -   uc    uuuau 
5'  gg     cccug     ug ggugaguuuugca ggauu gca  cggc     u
    ||     |||||     || ||||||||||||| ||||| |||  ||||     a
3'  cc     gggac     gc ucgcucaaaacgu ccuaa cgu  gucg     c
   a  aaaca     ----c  g             a     a   --    uacaa 
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Genome context
Coordinates (GRCz11; GCA_000002035.4) Overlapping transcripts
chr14: 31467026-31467130 [-]
KZ115452.1: 23130-23234 [-]
Clustered miRNAs
< 10kb from dre-mir-19c
dre-mir-18cchr14: 31467376-31467460 [-]
dre-mir-20bchr14: 31467167-31467260 [-]
dre-mir-19cchr14: 31467026-31467130 [-]
dre-mir-363chr14: 31466671-31466797 [-]
Database links

Mature sequence dre-miR-19c-5p

Accession MIMAT0031940

26 - 


 - 47

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Evidence not experimental
Database links

Mature sequence dre-miR-19c-3p

Accession MIMAT0001784
Previous IDsdre-miR-19c

64 - 


 - 86

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Evidence experimental; cloned [1]
Database links
Predicted targets


PMID:15937218 "The developmental miRNA profiles of zebrafish as determined by small RNA cloning" Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T Genes Dev. 19:1288-1293(2005).