Stem-loop sequence dre-mir-138-1

AccessionMI0002002 (change log)
DescriptionDanio rerio miR-138-1 stem-loop
Gene family MIPF0000075; mir-138
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled miR-138. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

miR-138 is a family of microRNA precursors found in animals, including humans. MicroRNAs are typically transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. The excised region or, mature product, of the miR-138 precursor is the microRNA mir-138. miR-138 has been used as an example of the post-transcriptional regulation of miRNA, due to the finding that while the precursor is expressed ubiquitously, the mature product is found only in specific cell types.

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Stem-loop
   u   -   ug ag             uca     --a    a ac 
5'  gug ugc  c  cugguguugugaa   ggccg   uguc c  g
    ||| |||  |  |||||||||||||   |||||   |||| |   
3'  cac acg  g  gaccacaacacuu   ucggc   auag g  u
   a   c   gu -g             -ua     cca    c ac 
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Confidence Annotation confidence: high
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Genome context
Coordinates (GRCz11; GCA_000002035.4) Overlapping transcripts
chr18: 17580159-17580245 [+]
intergenic
Database links

Mature sequence dre-miR-138-5p

Accession MIMAT0001835
Previous IDsdre-miR-138
Sequence

11 - 

agcugguguugugaaucaggccg

 - 33

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Evidence experimental; cloned [1]

Mature sequence dre-miR-138-3p

Accession MIMAT0031973
Sequence

58 - 

gcuauuucacaacaccagggu

 - 78

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Evidence not experimental
Database links

References

1
PMID:15937218 "The developmental miRNA profiles of zebrafish as determined by small RNA cloning" Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T Genes Dev. 19:1288-1293(2005).