Stem-loop sequence dre-mir-203b

AccessionMI0002041 (change log)
DescriptionDanio rerio miR-203b stem-loop
Gene family MIPF0000108; mir-203
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled MiR-203. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

In molecular biology miR-203 is a short non-coding RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms, such as translational repression and Argonaute-catalyzed messenger RNA cleavage. miR-203 has been identified as a skin-specific microRNA, and it forms an expression gradient that defines the boundary between proliferative epidermal basal progenitors and terminally differentiating suprabasal cells. It has also been found upregulated in psoriasis and differentially expressed in some types of cancer.

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       - -    gc           c    g    a     cuu 
5' uccu c uuug  cgagugguucu aaca uuca caguu   u
   |||| | ||||  ||||||||||| |||| |||| |||||    
3' agga g agac  guucaccagga uugu aagu guuag   u
       a c    ua           c    a    -     uag 
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Genome context
Coordinates (GRCz11; GCA_000002035.4) Overlapping transcripts
chr20: 27405878-27405962 [+]
Database links

Mature sequence dre-miR-203b-5p

Accession MIMAT0003407
Previous IDsdre-miR-203b*

14 - 


 - 35

Get sequence
Evidence experimental; cloned [1]
Database links

Mature sequence dre-miR-203b-3p

Accession MIMAT0001865
Previous IDsdre-miR-203b

51 - 


 - 72

Get sequence
Evidence experimental; cloned [1]
Database links
Predicted targets


PMID:15937218 "The developmental miRNA profiles of zebrafish as determined by small RNA cloning" Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T Genes Dev. 19:1288-1293(2005).