Stem-loop sequence dre-mir-338-2

AccessionMI0002064 (change log)
DescriptionDanio rerio miR-338-2 stem-loop
Gene family MIPF0000097; mir-338
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled miR-338. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

miR-338 is a family of brain-specific microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interference. miR-338 is located in an intronic region within the gene for apoptosis-associated tyrosine kinase (AATK). It has been predicted that it may downregulate genes which have a downstream negative effect on AATK expression.

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Genome context
Coordinates (GRCz11; GCA_000002035.4) Overlapping transcripts
chr12: 17727528-17727651 [+]
OTTDART00000058131 ; si:ch73-95a24.1-001; intron 1
ENSDART00000152652 ; si:ch73-95a24.1-001; intron 1
Database links

Mature sequence dre-miR-338

Accession MIMAT0001873

71 - 


 - 92

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Evidence experimental; cloned [1]
Database links
Predicted targets


PMID:15937218 "The developmental miRNA profiles of zebrafish as determined by small RNA cloning" Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T Genes Dev. 19:1288-1293(2005).