Stem-loop sequence mmu-mir-466a

Accession

MI0002401

Previous IDs

mmu-mir-466

Symbol

MGI:Mirn466

Description

Mus musculus miR-466a stem-loop

Gene family

MIPF0000208; mir-466

Stem-loop

--ua       uua          c   --  -     g 
    uaugugu   ugugugugua aug  ua cauau u
    |||||||   |||||||||| |||  || |||||  
    auacaca   gcacauacau uac  au guaua g
caga       --c          a   cu  a     a 

Deep sequencing

7967 reads, 84 experiments

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

• Coordinates (GRCm38): chr2: 10507918-10507990 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000026263 ; Sfmbt2-001; intron 10

  ENSMUST00000041105 ; Sfmbt2-001; intron 10

  ENSMUST00000116594 ; Sfmbt2-201; intron 11

Clustered miRNAs

< 10kb from mmu-mir-466a

• mmu-mir-467a-9: chr2: 10498393-10498475 [+]
• mmu-mir-466b-2: chr2: 10498685-10498766 [+]
• mmu-mir-669a-10: chr2: 10498911-10498997 [+]
• mmu-mir-669a-11: chr2: 10501339-10501425 [+]
• mmu-mir-467a-10: chr2: 10503273-10503355 [+]
• mmu-mir-466b-3: chr2: 10503565-10503645 [+]
• mmu-mir-669a-12: chr2: 10503791-10503877 [+]
• mmu-mir-467e: chr2: 10505721-10505807 [+]
• mmu-mir-466p: chr2: 10506006-10506094 [+]
• mmu-mir-467d: chr2: 10507630-10507714 [+]
• mmu-mir-466a: chr2: 10507918-10507990 [+]
• mmu-mir-297c: chr2: 10509016-10509113 [+]
• mmu-mir-669c: chr2: 10509296-10509404 [+]
• mmu-mir-669a-2: chr2: 10510164-10510260 [+]
• mmu-mir-297b: chr2: 10511667-10511775 [+]
• mmu-mir-466d: chr2: 10511967-10512062 [+]
• mmu-mir-669m-1: chr2: 10512790-10512887 [+]
• mmu-mir-669m-2: chr2: 10513434-10513531 [+]
• mmu-mir-466n: chr2: 10513741-10513834 [+]
• mmu-mir-669o: chr2: 10514300-10514395 [+]
• mmu-mir-466g: chr2: 10514595-10514674 [+]
• mmu-mir-466h: chr2: 10514891-10514971 [+]
• mmu-mir-297a-3: chr2: 10515820-10515921 [+]
• mmu-mir-466l: chr2: 10516097-10516217 [+]
• mmu-mir-297a-4: chr2: 10517067-10517164 [+]
• mmu-mir-669i: chr2: 10517604-10517730 [+]

Database links

• ENTREZGENE: 723922;Mir466
• MGI: 3619454;Mirn466

Mature sequence mmu-miR-466a-5p

• Accession: MIMAT0004759
• Sequence: 11 - uauguguguguacauguacaua - 32
• Deep sequencing: 1432 reads, 46 experiments
• Evidence: experimental; cloned [2], Solexa [3-4]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-466a-5p
  • MICRORNA.ORG:mmu-miR-466a-5p
  • MIRDB:mmu-miR-466a-5p
  • RNA22-MMU:mmu-miR-466a-5p
  • TARGETSCAN-VERT:mmu-miR-466a-5p

Mature sequence mmu-miR-466a-3p

• Accession: MIMAT0002107
• Previous IDs: mmu-miR-466
• Sequence: 50 - uauacauacacgcacacauaaga - 72
• Deep sequencing: 6429 reads, 76 experiments
• Evidence: experimental; cloned [1-2], Solexa [3-4]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-466a-3p
  • MICRORNA.ORG:mmu-miR-466a-3p
  • MIRDB:mmu-miR-466a-3p
  • RNA22-MMU:mmu-miR-466a-3p
  • TARGETSCAN-VERT:mmu-miR-466a-3p

References

1. PMID:15901636 "MicroRNA Mirn122a reduces expression of the posttranscriptionally regulated germ cell transition protein 2 (Tnp2) messenger RNA (mRNA) by mRNA cleavage" Yu Z, Raabe T, Hecht NB Biol Reprod. 73:427-433(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).