Stem-loop sequence hsa-mir-487a

Accession

MI0002471 (change log)

Previous IDs

hsa-mir-487

Symbol

HGNC:MIR487A

Description

Homo sapiens miR-487a stem-loop

Gene family

MIPF0000018; mir-154

Literature search

14 open access papers mention hsa-mir-487a
(32 sentences)

Stem-loop

         u     g   uua      c    -    c   a 
5' gguacu gaaga ugg   ucccug ugug uucg uua u
   |||||| ||||| |||   |||||| |||| |||| ||| u
3' cuauga uuuuu acc   agggac auac aagc agu u
         c     g   uac      -    u    -   a 

Deep sequencing

3143 reads, 0 reads per million, 103 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr14: 101052446-101052525 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000414335 ; BEGAIN-006; intron 1

  ENST00000554140 ; BEGAIN-006; intron 1

Clustered miRNAs

< 10kb from hsa-mir-487a

• hsa-mir-1185-1: chr14: 101042977-101043062 [+]
• hsa-mir-1185-2: chr14: 101044198-101044283 [+]
• hsa-mir-381: chr14: 101045920-101045994 [+]
• hsa-mir-487b: chr14: 101046455-101046538 [+]
• hsa-mir-539: chr14: 101047321-101047398 [+]
• hsa-mir-889: chr14: 101047901-101047979 [+]
• hsa-mir-544a: chr14: 101048658-101048748 [+]
• hsa-mir-655: chr14: 101049550-101049646 [+]
• hsa-mir-487a: chr14: 101052446-101052525 [+]
• hsa-mir-382: chr14: 101054306-101054381 [+]
• hsa-mir-134: chr14: 101054687-101054759 [+]
• hsa-mir-668: chr14: 101055258-101055323 [+]
• hsa-mir-485: chr14: 101055419-101055491 [+]
• hsa-mir-323b: chr14: 101056219-101056300 [+]
• hsa-mir-154: chr14: 101059755-101059838 [+]
• hsa-mir-496: chr14: 101060573-101060674 [+]
• hsa-mir-377: chr14: 101062050-101062118 [+]

Database links

• EntrezGene:MIR487A
• HGNC:MIR487A
• RNAcentral:URS000070BFF5_9606
• miRBase Tracker:MI0002471

Mature sequence hsa-miR-487a-5p

• Accession: MIMAT0026559
• Sequence: 13 - gugguuaucccugcuguguucg - 34
• Deep sequencing: 1217 reads, 75 experiments
• Evidence: experimental; Illumina [4]
• Predicted targets:
  • TargetScanVert:hsa-miR-487a-5p
  • miRDB:hsa-miR-487a-5p

Mature sequence hsa-miR-487a-3p

• Accession: MIMAT0002178
• Previous IDs: hsa-miR-487
• Sequence: 49 - aaucauacagggacauccaguu - 70
• Deep sequencing: 1924 reads, 100 experiments
• Evidence: experimental; cloned [1-3], Northern [1], Illumina [4]
• Database links:
  • RNAcentral:URS000016FD1B_9606
• Predicted targets:
  • TargetScanVert:hsa-miR-487a-3p
  • miRDB:hsa-miR-487a-3p
  • microrna.org:hsa-miR-487a-3p

References

1. PMID:15978578 "Identification of human fetal liver miRNAs by a novel method" Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X FEBS Lett. 579:3849-3854(2005).
2. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:23034410 "Birth and expression evolution of mammalian microRNA genes" Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H Genome Res. 23:34-45(2013).