Stem-loop mml-mir-30b

Accession

MI0002502

Description

Macaca mulatta mml-mir-30b precursor miRNA

Literature search

3 open access papers mention mml-mir-30b
(19 sentences)

Sequence

28452 reads, 213 reads per million, 8 experiments

accaaguuucaguucaUGUAAACAUCCUACACUCAGCuguaauacauggauuggCUGGGAGGUGGAUGUUUACUUCagcugacuugga
.(((((..((((((...((((((((((.((.((((((((............))))))))..))))))))))))...))))))))))).

Structure

a     uu      caU          U  -A        uaaua 
 ccaag  ucaguu   GUAAACAUCC AC  CUCAGCug     c
 |||||  ||||||   |||||||||| ||  ||||||||      
 gguuc  agucga   CAUUUGUAGG UG  GGGUCggu     a
a     --      CUU          -  GA        uaggu 

Annotation confidence Medium

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [2]. The expression of this mature miRNA was validated by Miska et al [1].

Genome context

chr8: 134094376-134094463 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mml-mir-30b

Mature mml-miR-30b-5p

• Accession: MIMAT0002213
• Description: Macaca mulatta mml-miR-30b-5p mature miRNA
• Sequence: 17 - UGUAAACAUCCUACACUCAGC - 37
• Evidence: experimental ; cloned [1], Illumina [3]

Mature mml-miR-30b-3p

• Accession: MIMAT0026563
• Description: Macaca mulatta mml-miR-30b-3p mature miRNA
• Sequence: 55 - CUGGGAGGUGGAUGUUUACUUC - 76
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68


2. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45