miRBase entry: mml-mir-128a

Stem-loop mml-mir-128a


Accession
MI0002518
Description
Macaca mulatta mml-mir-128a precursor miRNA
Gene family
MIPF0000048; mir-128


Sequence

79758 reads, 472 reads per million, 9 experiments
ugagcuguuggauuCGGGGCCGUAGCACUGUCUGAGAgguuuacauuucUCACAGUGAACCGGUCUCUUUUucagcugcuuc
.((((.((((((...(((((((...((((((..(((((((....)))))))))))))...)))))))...)))))).)))).

Structure
u    u      uuC       UAG      CU       u 
 gagc guugga   GGGGCCG   CACUGU  GAGAggu u
 |||| ||||||   |||||||   ||||||  |||||||  
 uucg cgacuU   CUCUGGC   GUGACA  CUcuuua a
c    u      UUU       CAA      --       c 


Annotation confidence High
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [2]. The expression of this mature miRNA was validated by Miska et al [1].

Genome context
chr12: 21159071-21159152 [+]

Database links

Mature mml-miR-128a-3p

Accession MIMAT0002229
Description Macaca mulatta mml-miR-128a-3p mature miRNA
Sequence 50 - UCACAGUGAACCGGUCUCUUUU - 71
Evidence experimental
cloned [1], Illumina [3]
Database links
Predicted targets

Mature mml-miR-128a-5p

Accession MIMAT0026565
Description Macaca mulatta mml-miR-128a-5p mature miRNA
Sequence 15 - CGGGGCCGUAGCACUGUCUGAGA - 37
Evidence experimental
Illumina [3]

References

  1. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68

  2. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24

  3. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45