miRBase entry: mml-mir-34a

Stem-loop mml-mir-34a


Accession
MI0002801
Description
Macaca mulatta mml-mir-34a precursor miRNA
Gene family
MIPF0000039; mir-34

Literature search
4 open access papers mention mml-mir-34a
(8 sentences)

Sequence

4616 reads, 43 reads per million, 9 experiments
ggccagcugugaguguuucuuUGGCAGUGUCUUAGCUGGUUGUugugagcaauaguaaggaagcAAUCAGCAAGUAUACUGCCCUAgaagugcuacacauuguggggccu
((((.(((((((((((((((..(((((((((((.((((((((((....((....)).....))))))))))))).))))))))..))))))))).))))..))..)))).

Structure
-    -a  --    -         uU        -   A          -guga  a 
 ggcc  gc  ugug aguguuucu  GGCAGUGU CUU GCUGGUUGUu     gc a
 ||||  ||  |||| |||||||||  |||||||| ||| ||||||||||     ||  
 ccgg  ug  acac ucgugaagA  CCGUCAUA GAA CGACUAAcga     ug u
u    gg  uu    a         UC        U   -          aggaa  a 


Annotation confidence Not enough data
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Comments
Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context
chr1: 8320927-8321036 [-]

Database links

Mature mml-miR-34a-5p

Accession MIMAT0002499
Description Macaca mulatta mml-miR-34a-5p mature miRNA
Sequence 22 - UGGCAGUGUCUUAGCUGGUUGU - 43
Evidence experimental
Illumina [2]
Database links
Predicted targets

Mature mml-miR-34a-3p

Accession MIMAT0026586
Description Macaca mulatta mml-miR-34a-3p mature miRNA
Sequence 65 - AAUCAGCAAGUAUACUGCCCUA - 86
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24

  2. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45