Stem-loop sequence mml-mir-181a-2

Accession

MI0002808 (change log)

Previous IDs

mml-mir-181a

Description

Macaca mulatta miR-181a-2 stem-loop

Gene family

MIPF0000007; mir-181

Literature search

3 open access papers mention mml-mir-181a-2
(33 sentences)

Stem-loop

   agaagggcuaucaggccagccuuca         a   a   u      cu       a    ggga 
5'                          gaggacucc agg aca ucaacg  gucggug guuu    u
                            ||||||||| ||| ||| ||||||  ||||||| ||||    u
3'                          uuccugggg ucc ugu aguugc  cagucac caaa    u
   ------------------------a         c   a   c      --       -    aaag 

Deep sequencing

2586412 reads, 1.51e+04 reads per million, 9 experiments

Confidence

Annotation confidence: not enough data

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Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [2]. The expression of this mature miRNA was validated by Miska et al [1].

Genome context

• Coordinates (Mmul_8.0.1; GCA_000772875.3): chr15: 14342713-14342822 [-]
• Overlapping transcripts:

  sense

  ENSMMUT00000022186 ; AUH-201; intron 3

  ENSMMUT00000045783 ; AUH-202; intron 3

Clustered miRNAs

< 10kb from mml-mir-181a-2

• mml-mir-181a-2: chr15: 14342713-14342822 [-]
• mml-mir-181b-2: chr15: 14341488-14341576 [-]

Database links

• EntrezGene:MIR181A-2
• RNAcentral:URS00001F8A34_9544
• miRBase Tracker:MI0002808

Mature sequence mml-miR-181a-5p

• Accession: MIMAT0002506
• Previous IDs: mml-miR-181a
• Sequence: 39 - aacauucaacgcugucggugagu - 61
• Deep sequencing: 5130597 reads, 9 experiments
• Evidence: by similarity; MI0000289
• Database links:
  • RNAcentral:URS00003DA300_9544
• Predicted targets:
  • TargetScanVert:mml-miR-181a-5p

References

1. PMID:15345052 "Microarray analysis of microRNA expression in the developing mammalian brain" Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR Genome Biol. 5:R68(2004).
2. PMID:15652478 "Phylogenetic shadowing and computational identification of human microRNA genes" Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E Cell. 120:21-24(2005).