Stem-loop sequence hsa-mir-520e

Accession

MI0003143 (change log)

Symbol

HGNC:MIR520E

Description

Homo sapiens miR-520e stem-loop

Gene family

MIPF0000020; mir-515

Literature search

40 open access papers mention hsa-mir-520e
(95 sentences)

Stem-loop

       cu  u             u       g     guug   g 
5' ucuc  gc gugacccucaaga ggaagca uuucu    ucu a
   ||||  || ||||||||||||| ||||||| |||||    |||  
3' agag  ug cauugggaguuuu ccuucgu aaaga    agg a
       uu  u             u       g     ---a   a 

Deep sequencing

1524 reads, 33.3 reads per million, 36 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr19: 53675711-53675797 [+]
• Overlapping transcripts:

  antisense

  OTTHUMT00000464179 ; ZNF665-002; intron 1

  OTTHUMT00000464180 ; ZNF665-001; intron 3

  ENST00000600412 ; ZNF665-002; intron 1

  ENST00000396424 ; ZNF665-001; intron 3

Clustered miRNAs

< 10kb from hsa-mir-520e

• hsa-mir-512-1: chr19: 53666679-53666762 [+]
• hsa-mir-512-2: chr19: 53669157-53669254 [+]
• hsa-mir-1323: chr19: 53671968-53672040 [+]
• hsa-mir-498: chr19: 53674197-53674320 [+]
• hsa-mir-520e: chr19: 53675711-53675797 [+]
• hsa-mir-515-1: chr19: 53679003-53679085 [+]
• hsa-mir-519e: chr19: 53679940-53680023 [+]
• hsa-mir-520f: chr19: 53682159-53682245 [+]
• hsa-mir-515-2: chr19: 53685009-53685091 [+]

Database links

• EntrezGene:MIR520E
• HGNC:MIR520E
• miRBase Tracker:MI0003143

Mature sequence hsa-miR-520e-5p

• Accession: MIMAT0037324
• Sequence: 16 - cucaagauggaagcaguuucug - 37
• Deep sequencing: 5 reads, 3 experiments
• Evidence: experimental; Illumina [2]

Mature sequence hsa-miR-520e-3p

• Accession: MIMAT0002825
• Sequence: 54 - aaagugcuuccuuuuugaggg - 74
• Deep sequencing: 1510 reads, 42 experiments
• Evidence: experimental; array-cloned [1]
• Predicted targets:
  • TargetScanVert:hsa-miR-520e
  • miRDB:hsa-miR-520e-3p
  • microrna.org:hsa-miR-520e-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:25822230 "Selective microRNA-Offset RNA expression in human embryonic stem cells" Asikainen S, Heikkinen L, Juhila J, Holm F, Weltner J, Trokovic R, Mikkola M, Toivonen S, Balboa D, Lampela R, Icay K, Tuuri T, Otonkoski T, Wong G, Hovatta O PLoS One. 10:e0116668(2015).