Stem-loop hsa-mir-519e

Accession

MI0003145

Symbol

HGNC: MIR519E

Description

Homo sapiens hsa-mir-519e precursor miRNA

Literature search

24 open access papers mention hsa-mir-519e
(62 sentences)

Sequence

6 reads, 2 reads per million, 4 experiments

ucucaugcagucaUUCUCCAAAAGGGAGCACUUUCuguuugaaagaaaacaAAGUGCCUCCUUUUAGAGUGUUacuguuugaga
(((((.(((((.((.(((.(((((((.((((((..(((((......))))))))))).))))))).))).)).))))).)))))

Structure

     u     c  U   C       A      UC     ga 
ucuca gcagu aU CUC AAAAGGG GCACUU  uguuu  a
||||| ||||| || ||| ||||||| ||||||  |||||   
agagu uguca UG GAG UUUUCCU CGUGAA  acaaa  a
     u     U  U   A       C      --     ag 

Annotation confidence Not enough data

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context

chr19: 53679940-53680023 [+]

Clustered miRNAs

8 other miRNAs are < 10 kb from hsa-mir-519e

Disease association

hsa-mir-519e is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-519e-5p

• Accession: MIMAT0002828
• Description: Homo sapiens hsa-miR-519e-5p mature miRNA
• Sequence: 14 - UUCUCCAAAAGGGAGCACUUUC - 35
• Evidence: experimental ; array-cloned [1]

Mature hsa-miR-519e-3p

• Accession: MIMAT0002829
• Description: Homo sapiens hsa-miR-519e-3p mature miRNA
• Sequence: 52 - AAGUGCCUCCUUUUAGAGUGUU - 73
• Evidence: experimental ; array-cloned [1], cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770