miRBase entry: hsa-mir-523

Stem-loop hsa-mir-523


Accession
MI0003153
Symbol
HGNC: MIR523
Description
Homo sapiens hsa-mir-523 precursor miRNA mir-515
Gene
family?
RF00639; mir-515

Literature search
4 open access papers mention hsa-mir-523
(10 sentences)

Sequence

107 reads, 2 reads per million, 19 experiments
ucucaugcugugaccCUCUAGAGGGAAGCGCUUUCUGuugucugaaagaaaaGAACGCGCUUCCCUAUAGAGGGUuacccuuugaga
(((((....(((((((((((.((((((((((.((((....(((...)))..)))).)))))))))).)))))))))))....)))))

Structure
     ugcu           G          U    Guug   g 
ucuca    gugaccCUCUA AGGGAAGCGC UUCU    ucu  
|||||    ||||||||||| |||||||||| ||||    ||| a
agagu    cauUGGGAGAU UCCCUUCGCG AAGa    aga  
     uucc           A          C    --aa   a 


Annotation confidence High
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Genome context
chr19: 53698385-53698471 [+]
Clustered miRNAs
10 other miRNAs are < 10 kb from hsa-mir-523
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-523 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-523-5p

Accession MIMAT0005449
Description Homo sapiens hsa-miR-523-5p mature miRNA
Sequence 16 - CUCUAGAGGGAAGCGCUUUCUG - 37
Evidence experimental
array-cloned [1], cloned [2]
Database links
Predicted targets

Mature hsa-miR-523-3p

Accession MIMAT0002840
Description Homo sapiens hsa-miR-523-3p mature miRNA
Sequence 53 - GAACGCGCUUCCCUAUAGAGGGU - 75
Evidence experimental
array-cloned [1], cloned [2]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 15965474
    Identification of hundreds of conserved and nonconserved human microRNAs
    "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
    "Nat Genet (2005) 37:766-770