Stem-loop hsa-mir-521-1

Accession

MI0003176

Symbol

HGNC: MIR521-1

Description

Homo sapiens hsa-mir-521-1 precursor miRNA mir-515

Gene
family

RF00639; mir-515

Literature search

10 open access papers mention hsa-mir-521-1
(15 sentences)

Sequence

12 reads, 1 reads per million, 8 experiments

ucucaggcugugacccuccaaagggaagaacuuucuguugucuaaaagaaaagAACGCACUUCCCUUUAGAGUGUuaccgugugaga
(((((.((.(((((.(((.(((((((((..(.((((....(((...)))..)))).)..))))))))).))).))))).)).)))))

Structure

     g  u     c   c         aa u    guug   a 
ucuca gc gugac cuc aaagggaag  c uucu    ucu  
||||| || ||||| ||| |||||||||  | ||||    ||| a
agagu ug cauUG GAG UUUCCCUUC  G AAga    aga  
     g  c     U   A         AC C    --aa   a 

Annotation confidence Low

Genome context

chr19: 53748636-53748722 [+]

Clustered miRNAs

8 other miRNAs are < 10 kb from hsa-mir-521-1

Disease association

hsa-mir-521-1 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-521

• Accession: MIMAT0002854
• Description: Homo sapiens hsa-miR-521 mature miRNA
• Sequence: 54 - AACGCACUUCCCUUUAGAGUGU - 75
• Evidence: experimental ; array-cloned [1], cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770