miRBase entry: mmu-mir-539

Stem-loop mmu-mir-539


Accession
MI0003520
Symbol
MGI: Mir539
Description
Mus musculus mmu-mir-539 precursor miRNA
Gene family
MIPF0000018; mir-154

Literature search
11 open access papers mention mmu-mir-539
(18 sentences)

Sequence

2628 reads, 144 reads per million, 49 experiments
uacuugaGGAGAAAUUAUCCUUGGUGUGUuggcucuuuuggaugaauCAUACAAGGAUAAUUUCUUUUUgagua
(((((((((((((((((((((((.((((((.(.(((...)))).)).)))))))))))))))))))))))))))

Structure
                       G    -  g c   u 
uacuugaGGAGAAAUUAUCCUUG UGUG Uu g ucu  
||||||||||||||||||||||| |||| || | ||| u
augagUUUUUCUUUAAUAGGAAC AUAC aa u agg  
                       -    u  g -   u 


Annotation confidence High
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Genome context
chr12: 109728129-109728202 [+]
Clustered miRNAs
15 other miRNAs are < 10 kb from mmu-mir-539
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-539-5p

Accession MIMAT0003169
Description Mus musculus mmu-miR-539-5p mature miRNA
Sequence 8 - GGAGAAAUUAUCCUUGGUGUGU - 29
Evidence experimental
MPSS [2], miRAP-cloned [3], Illumina [4-5]
Database links
Predicted targets

Mature mmu-miR-539-3p

Accession MIMAT0017208
Description Mus musculus mmu-miR-539-3p mature miRNA
Sequence 48 - CAUACAAGGAUAAUUUCUUUUU - 69
Evidence experimental
Illumina [5]
Database links
Predicted targets

References

  1. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  2. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  3. PubMed ID: 16582102
    The expression profile of microRNAs in mouse embryos
    "Mineno J, Okamoto S, Ando T, Sato M, Chono H, Izu H, Takayama M, Asada K, Mirochnitchenko O, Inouye M, Kato I"
    "Nucleic Acids Res (2006) 34:1765-1771

  4. PubMed ID: 16274478
    Identification of clustered microRNAs using an ab initio prediction method
    Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
    BMC Bioinformatics (2005) 6:267

  5. PubMed ID: 16973894
    Mouse microRNA profiles determined with a new and sensitive cloning method
    "Takada S, Berezikov E, Yamashita Y, Lagos-Quintana M, Kloosterman WP, Enomoto M, Hatanaka H, Fujiwara S, Watanabe H, Soda M, Choi YL, Plasterk RH, Cuppen E, Mano H"
    "Nucleic Acids Res (2006) 34:e115