Stem-loop sequence mmu-mir-291b

Accession

MI0003539 (change log)

Symbol

MGI:Mir291b

Description

Mus musculus miR-291b stem-loop

Gene family

MIPF0000068; mir-290

Literature search

21 open access papers mention mmu-mir-291b
(140 sentences)

Stem-loop

           u u   u         g  - c cu    gg 
5' acauacag g cga caaagugga gc c u  ccgc  c
   |||||||| | ||| ||||||||| || | |  ||||   
3' uguguguc c guu guuuuaccu cg g a  ggcg  u
           u u   u         a  u a ag    gu 

Deep sequencing

46480 reads, 502 reads per million, 43 experiments

Confidence

Annotation confidence: high

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Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr7: 3219482-3219560 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-291b

• mmu-mir-290a: chr7: 3218626-3218708 [+]
• mmu-mir-290b: chr7: 3218638-3218695 [-]
• mmu-mir-291a: chr7: 3218919-3219000 [+]
• mmu-mir-292a: chr7: 3219189-3219270 [+]
• mmu-mir-292b: chr7: 3219198-3219259 [-]
• mmu-mir-291b: chr7: 3219482-3219560 [+]
• mmu-mir-293: chr7: 3220343-3220422 [+]
• mmu-mir-294: chr7: 3220641-3220724 [+]
• mmu-mir-295: chr7: 3220773-3220841 [+]

Database links

• EntrezGene:Mirn291b
• MGI:Mir291b
• RNAcentral:URS00006DFEE9_10090
• miRBase Tracker:MI0003539

Mature sequence mmu-miR-291b-5p

• Accession: MIMAT0003189
• Sequence: 13 - gaucaaaguggaggcccucucc - 34
• Deep sequencing: 40411 reads, 38 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00000440CB_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-291b-5p
  • miRDB:mmu-miR-291b-5p
  • microrna.org:mmu-miR-291b-5p

Mature sequence mmu-miR-291b-3p

• Accession: MIMAT0003190
• Sequence: 48 - aaagugcauccauuuuguuugu - 69
• Deep sequencing: 6066 reads, 25 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00005352B1_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-291b-3p
  • miRDB:mmu-miR-291b-3p
  • microrna.org:mmu-miR-291b-3p

References

1. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).