Stem-loop mmu-mir-291b

Accession

MI0003539

Symbol

MGI: Mir291b

Description

Mus musculus mmu-mir-291b precursor miRNA

Gene family

MIPF0000068; mir-290

Literature search

21 open access papers mention mmu-mir-291b
(143 sentences)

Sequence

9951 reads, 561 reads per million, 44 experiments

acauacagugucGAUCAAAGUGGAGGCCCUCUCCgcggcuuggcgggAAAGUGCAUCCAUUUUGUUUGUcucugugugu
((((((((.(.(((.(((((((((.((.((.(((((......)))))..)).)).))))))))).))).).))))))))

Structure

        u u   U         G  C  -C     gg 
acauacag g cGA CAAAGUGGA GC CU  UCCgc  c
|||||||| | ||| ||||||||| || ||  |||||   
uguguguc c GUU GUUUUACCU CG GA  gggcg  u
        u U   U         A  U  AA     gu 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr7: 3219482-3219560 [+]

Clustered miRNAs

8 other miRNAs are < 10 kb from mmu-mir-291b

Mature mmu-miR-291b-5p

• Accession: MIMAT0003189
• Description: Mus musculus mmu-miR-291b-5p mature miRNA
• Sequence: 13 - GAUCAAAGUGGAGGCCCUCUCC - 34
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

Mature mmu-miR-291b-3p

• Accession: MIMAT0003190
• Description: Mus musculus mmu-miR-291b-3p mature miRNA
• Sequence: 48 - AAAGUGCAUCCAUUUUGUUUGU - 69
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267