Stem-loop sequence hsa-mir-548c

Accession

MI0003630 (change log)

Symbol

HGNC:MIR548C

Description

Homo sapiens miR-548c stem-loop

Gene family

MIPF0000317; mir-548

Literature search

58 open access papers mention hsa-mir-548c
(254 sentences)

Stem-loop

   cauuggcauc                         c         cau   u 
5'           uauuagguuggugcaaaaguaauug gguuuuugc   uac u
             ||||||||||||||||||||||||| |||||||||   ||| u
3'           auaauucaaccacguuuucauuaac cuaaaaacg   aug c
   -------uuc                         u         ---   a 

Deep sequencing

15537 reads, 13.5 reads per million, 156 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Comments

Extensive cloning studies suggest that the 5' miRNA may be the predominant one [2].

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr12: 64622509-64622605 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000401052 ; RPS11P6-004; intron 2

  ENST00000535684 ; RPS11P6-004; intron 2

Clustered miRNAs

< 10kb from hsa-mir-548c

• hsa-mir-548c: chr12: 64622509-64622605 [+]
• hsa-mir-548z: chr12: 64622509-64622605 [-]

Database links

• EntrezGene:MIR548C
• HGNC:MIR548C
• RNAcentral:URS000075DBE5_9606
• miRBase Tracker:MI0003630

Mature sequence hsa-miR-548c-5p

• Accession: MIMAT0004806
• Sequence: 25 - aaaaguaauugcgguuuuugcc - 46
• Deep sequencing: 14743 reads, 154 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS00002C02E4_9606
• Predicted targets:
  • TargetMiner:hsa-miR-548c-5p
  • TargetScanVert:hsa-miR-548c-5p
  • miRDB:hsa-miR-548c-5p
  • microrna.org:hsa-miR-548c-5p

Mature sequence hsa-miR-548c-3p

• Accession: MIMAT0003285
• Previous IDs: hsa-miR-548c
• Sequence: 61 - caaaaaucucaauuacuuuugc - 82
• Deep sequencing: 285 reads, 62 experiments
• Evidence: experimental; SAGE [1]
• Predicted targets:
  • TargetScanVert:hsa-miR-548c-3p
  • miRDB:hsa-miR-548c-3p
  • microrna.org:hsa-miR-548c-3p

References

1. PMID:16505370 "The colorectal microRNAome" Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE Proc Natl Acad Sci U S A. 103:3687-3692(2006).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).