Stem-loop hsa-mir-642a

Accession

MI0003657

Symbol

HGNC: MIR642A

Description

Homo sapiens hsa-mir-642a precursor miRNA mir-642

Gene
family

RF00963; mir-642

Literature search

9 open access papers mention hsa-mir-642a
(64 sentences)

Sequence

1002 reads, 11 reads per million, 91 experiments

aucugaguugggaggGUCCCUCUCCAAAUGUGUCUUGgggugggggaucaAGACACAUUUGGAGAGGGAACCucccaacucggccucugccaucauu
....(((((((((((.((((((((((((((((((((((.........)))))))))))))))))))))).)))))))))))(((....)))......

Structure

------------aucu           G                      ggu 
                gaguugggagg UCCCUCUCCAAAUGUGUCUUGg   g
                ||||||||||| ||||||||||||||||||||||   g
                cucaacccuCC AGGGAGAGGUUUACACAGAacu   g
uuacuaccgucuccgg           A                      agg 

Annotation confidence High

Genome context

chr19: 45674928-45675024 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-642a

Disease association

hsa-mir-642a is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-642a-5p

• Accession: MIMAT0003312
• Description: Homo sapiens hsa-miR-642a-5p mature miRNA
• Sequence: 16 - GUCCCUCUCCAAAUGUGUCUUG - 37
• Evidence: experimental ; RT-PCR [1], SAGE [1], cloned [2]

Mature hsa-miR-642a-3p

• Accession: MIMAT0020924
• Description: Homo sapiens hsa-miR-642a-3p mature miRNA
• Sequence: 51 - AGACACAUUUGGAGAGGGAACC - 72
• Evidence: experimental ; SOLiD [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16505370
   The colorectal microRNAome
   "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
   "Proc Natl Acad Sci U S A (2006) 103:3687-3692


3. PubMed ID: 21767385
   Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis
   Zaragosi LE, Wdziekonski B, Brigand KL, Villageois P, Mari B, Waldmann R, Dani C, Barbry P
   Genome Biol (2011) 12:R64