miRBase entry: hsa-mir-670

Stem-loop hsa-mir-670


Accession
MI0003933
Symbol
HGNC: MIR670
Description
Homo sapiens hsa-mir-670 precursor miRNA
Gene family
MIPF0000734; mir-670

Literature search
2 open access papers mention hsa-mir-670
(2 sentences)

Sequence

105 reads, 19 reads per million, 12 experiments
guuuagggguggaccugauGUCCCUGAGUGUAUGUGGUGaaccugaauuugccuugggUUUCCUCAUAUUCAUUCAGGAgugucaguugccccuucac
((..((((((((..((((((.(((((((((.((((((.((((((((.......)))))))).).))))).)))))))).)))))))))))))))..))

Structure
  uu        ac      U -        U     - U        au 
gu  aggggugg  cugauG C CCUGAGUG AUGUG G Gaaccuga  u
||  ||||||||  |||||| | |||||||| ||||| | ||||||||  u
ca  uccccguu  gacugu g GGACUUAC UAUAC C UUUggguu  g
  cu        --      - A        U     U C        cc 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
Berezikov et al. proposed this sequence as a miRNA candidate based on the RAKE method [1]. Artzi et al. later showed that it is a homolog of a validated miRNA in mouse [2].

Genome context
chr11: 43559656-43559753 [+]

Disease association
hsa-mir-670 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-670-5p

Accession MIMAT0010357
Description Homo sapiens hsa-miR-670-5p mature miRNA
Sequence 20 - GUCCCUGAGUGUAUGUGGUG - 39
Evidence experimental
RAKE [1], Illumina [3]

Mature hsa-miR-670-3p

Accession MIMAT0026640
Description Homo sapiens hsa-miR-670-3p mature miRNA
Sequence 59 - UUUCCUCAUAUUCAUUCAGGA - 79
Evidence experimental
Illumina [3]

References

  1. PubMed ID: 16954537
    Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
    "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
    "Genome Res (2006) 16:1289-1298

  2. PubMed ID: 18215311
    miRNAminer: a tool for homologous microRNA gene search
    "Artzi S, Kiezun A, Shomron N"
    "BMC Bioinformatics (2008) 9:39

  3. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45