miRBase entry: hsa-mir-759

Stem-loop hsa-mir-759


Accession
MI0004065
Symbol
HGNC: MIR759
Description
Homo sapiens hsa-mir-759 precursor miRNA
Gene family
MIPF0000706; mir-759


Sequence

uaauaaauuaaaugccuaaacugGCAGAGUGCAAACAAUUUUGACucagaucuaaauguuugcacuggcuguuuaaacauuuaauuuguua
((((((((((((((..(((((.(((..((((((((((.(((.((......)).))))))))))))).))))))))..))))))))))))))

Structure
              cc     u   AG          A   U  Cu 
uaauaaauuaaaug  uaaac gGC  AGUGCAAACA UUU GA  c
||||||||||||||  ||||| |||  |||||||||| ||| ||   
auuguuuaauuuac  auuug ucg  ucacguuugu aaa cu  a
              aa     -   -g          -   u  ag 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
Berezikov et al. proposed this sequence as a miRNA candidate based on the RAKE method [1]. Artzi et al. later showed that it is a homolog of a validated miRNA in mouse [2].

Genome context
chr13: 52810050-52810140 [+]

Disease association
hsa-mir-759 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-759

Accession MIMAT0010497
Description Homo sapiens hsa-miR-759 mature miRNA
Sequence 24 - GCAGAGUGCAAACAAUUUUGAC - 45
Evidence experimental
RAKE [1]

References

  1. PubMed ID: 16954537
    Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
    "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
    "Genome Res (2006) 16:1289-1298

  2. PubMed ID: 18215311
    miRNAminer: a tool for homologous microRNA gene search
    "Artzi S, Kiezun A, Shomron N"
    "BMC Bioinformatics (2008) 9:39