Stem-loop sequence mmu-mir-758

Accession

MI0004129

Symbol

MGI:Mir758

Description

Mus musculus miR-758 stem-loop

Gene family

MIPF0000126; mir-379

Stem-loop

       g     --    u      aga   c   c   a 
ugggugc ugagg  uggu gaccag   gca acg uau u
||||||| |||||  |||| ||||||   ||| ||| |||  
aucuaug acucc  auca cugguc   ugu ugc gug u
       -     ca    c      cag   u   c   u 

Deep sequencing

1273 reads, 34 experiments

Genome context

• Coordinates (GRCm38): chr12: 109712810-109712890 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-758

• mmu-mir-379: chr12: 109709060-109709125 [+]
• mmu-mir-411: chr12: 109710175-109710256 [+]
• mmu-mir-299a: chr12: 109710638-109710700 [+]
• mmu-mir-299b: chr12: 109710645-109710693 [-]
• mmu-mir-380: chr12: 109711803-109711863 [+]
• mmu-mir-1197: chr12: 109712317-109712436 [+]
• mmu-mir-323: chr12: 109712508-109712593 [+]
• mmu-mir-758: chr12: 109712810-109712890 [+]
• mmu-mir-329: chr12: 109713481-109713577 [+]
• mmu-mir-494: chr12: 109715318-109715402 [+]
• mmu-mir-679: chr12: 109715577-109715650 [+]
• mmu-mir-1193: chr12: 109715671-109715791 [+]
• mmu-mir-666: chr12: 109717085-109717183 [+]
• mmu-mir-543: chr12: 109717258-109717333 [+]
• mmu-mir-495: chr12: 109718754-109718816 [+]
• mmu-mir-667: chr12: 109720006-109720097 [+]
• mmu-mir-376c: chr12: 109722718-109722803 [+]

Database links

• ENTREZGENE: 791071;Mir758
• MGI: 3691604;Mir758

Mature sequence mmu-miR-758-5p

• Accession: MIMAT0017235
• Previous IDs: mmu-miR-758*
• Sequence: 14 - ugguugaccagagagcacacg - 34
• Deep sequencing: 100 reads, 12 experiments
• Evidence: experimental; Solexa [4]
• Predicted targets:
  • DIANA-MICROT:mmu-miR-758-5p
  • MIRDB:mmu-miR-758-5p
  • RNA22-MMU:mmu-miR-758-5p

Mature sequence mmu-miR-758-3p

• Accession: MIMAT0003889
• Previous IDs: mmu-miR-758
• Sequence: 49 - uuugugaccugguccacua - 67
• Deep sequencing: 1172 reads, 29 experiments
• Evidence: experimental; cloned [1], 454 [2], Solexa [3-4]
• Validated targets:
  • TARBASE:mmu-miR-758-3p
• Predicted targets:
  • DIANA-MICROT:mmu-miR-758-3p
  • MICRORNA.ORG:mmu-miR-758-3p
  • MIRDB:mmu-miR-758-3p
  • RNA22-MMU:mmu-miR-758-3p
  • TARGETSCAN-VERT:mmu-miR-758

References

1. PMID:16954537 "Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis" Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E Genome Res. 16:1289-1298(2006).
2. PMID:17989215 "RNA sequence analysis defines Dicer's role in mouse embryonic stem cells" Calabrese JM, Seila AC, Yeo GW, Sharp PA Proc Natl Acad Sci U S A. 104:18097-18102(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).