Stem-loop sequence xtr-mir-27b

AccessionMI0004810 (change log)
DescriptionXenopus tropicalis miR-27b stem-loop
Gene family MIPF0000036; mir-27
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled miR-27. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

miR-27 is a family of microRNA precursors found in animals, including humans. MicroRNAs are typically transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. The excised region or, mature product, of the miR-27 precursor is the microRNA mir-27. Herpesvirus saimiri expresses several non-coding RNAs (HSURs) which have been found to significantly reduce the level of mir-27 in a host cell. It has been proposed that miR-27 operates together with miR-23 and mir-24 in a co-operative cluster.

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Stem-loop
   -a       acca                  auug        u  uug 
5'   ccuuucu    aggugcagagcuuagcug    gugaacag ga   a
     |||||||    ||||||||||||||||||    |||||||| ||   u
3'   ggagaga    uccacgucuugaaucggu    cacuuguu cu   u
   cg       --ag                  --ga        u  ccc 
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Confidence
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Genome context
Coordinates (Xenopus_tropicalis_v9.1; GCA_000004195.3) Overlapping transcripts
chr1: 123463698-123463793 [+]
intergenic
Clustered miRNAs
< 10kb from xtr-mir-27b
xtr-mir-23bchr1: 123463474-123463561 [+]
xtr-mir-27bchr1: 123463698-123463793 [+]
xtr-mir-24achr1: 123464315-123464381 [+]
Database links

Mature sequence xtr-miR-27b

Accession MIMAT0003571
Sequence

61 - 

uucacaguggcuaaguucugc

 - 81

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Evidence by similarity; MI0000440
Predicted targets