Stem-loop sequence xtr-mir-34b-4

AccessionMI0004818 (change log)
DescriptionXenopus tropicalis miR-34b-4 stem-loop
Gene family MIPF0000039; mir-34
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-34_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The mir-34 microRNA precursor family are non-coding RNA molecules that, in mammals, give rise to three major mature miRNAs. The miR-34 family members were discovered computationally and later verified experimentally. The precursor miRNA stem-loop is processed in the cytoplasm of the cell, with the predominant miR-34 mature sequence excised from the 5' arm of the hairpin. The mature miR-34a is a part of the p53 tumor suppressor network; therefore, it is hypothesized that miR-34 dysregulation is involved in the development of some cancers.

Show Wikipedia entry View @ Wikipedia Edit Wikipedia entry
   --uuca  c   g       c        uuaua 
5'       gg agu uaguuag ugauugug     u
         || ||| ||||||| ||||||||      
3'       cc uca aucgauc acuaacgu     c
   aaaaua  a   a       -        uuaaa 
Get sequence
Feedback: Do you believe this miRNA is real?
Database links

Mature sequence xtr-miR-34b

Accession MIMAT0003579

3 - 


 - 25

Get sequence
Evidence by similarity; MI0003690
Predicted targets