Stem-loop sequence xtr-mir-129-1

AccessionMI0004829 (change log)
DescriptionXenopus tropicalis miR-129-1 stem-loop
Gene family MIPF0000073; mir-129
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-129_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

The miR-129 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. This microRNA was first experimentally characterised in mouse and homologues have since been discovered in several other species, such as humans, rats and zebrafish. The mature sequence is excised by the Dicer enzyme from the 5' arm of the hairpin. It was elucidated by Calin et al. that miR-129-1 is located in a fragile site region of the human genome near a specific site, FRA7H in chromosome 7q32, which is a site commonly deleted in many cancers. miR-129-2 is located in 11p11.2.

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   -       u     -       c   cu      g   ua  uaa 
5'  guccuuc caaau cuuuuug ggu  gggcuu cug  ug   a
    ||||||| ||||| ||||||| |||  |||||| |||  ||    
3'  cgggagg guuua gaaaaac cca  cccgaa ggc  au   u
   g       c     c       c   uu      g   cg  cca 
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Genome context
Coordinates (Xenopus_tropicalis_v9.1; GCA_000004195.3) Overlapping transcripts
chr4: 3080976-3081065 [+]
Database links

Mature sequence xtr-miR-129

Accession MIMAT0003590

14 - 


 - 34

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Evidence by similarity; MI0001983
Predicted targets