Stem-loop sequence xtr-mir-133c

AccessionMI0004835 (change log)
DescriptionXenopus tropicalis miR-133c stem-loop
Gene family MIPF0000029; mir-133
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled mir-133_microRNA_precursor_family. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

mir-133 is a type of non-coding RNA called a microRNA that was first experimentally characterised in mice. Homologues have since been discovered in several other species including invertebrates such as the fruitfly Drosophila melanogaster. Each species often encodes multiple microRNAs with identical or similar mature sequence. For example, in the human genome there are three known miR-133 genes: miR-133a-1, miR-133a-2 and miR-133b found on chromosomes 18, 20 and 6 respectively. The mature sequence is excised from the 3' arm of the hairpin. miR-133 is expressed in muscle tissue and appears to repress the expression of non-muscle genes.

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   --     uuu   aa       aa  u  a        aacug 
5'   aaugc   gcu  agcuggu  aa gg accaaauc     u
     |||||   |||  |||||||  || || ||||||||      
3'   uuacg   cga  ucgacca  uu cc ugguuuag     u
   ag     ugu   cg       ac  c  c        guaag 
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Genome context
Coordinates (Xenopus_tropicalis_v9.1; GCA_000004195.3) Overlapping transcripts
KV460667.1: 81387-81472 [-]
Database links

Mature sequence xtr-miR-133c

Accession MIMAT0003595

52 - 


 - 73

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Evidence by similarity; MI0001992
Predicted targets