Stem-loop sequence xtr-mir-210

AccessionMI0004864 (change log)
DescriptionXenopus tropicalis miR-210 stem-loop
Gene family MIPF0000086; mir-210
Community annotation

This text is a summary paragraph taken from the Wikipedia entry entitled Mir-210_microRNA. miRBase and Rfam are facilitating community annotation of microRNA families and entries in Wikipedia. Read more ...

In molecular biology mir-210 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. mir-210 has been strongly linked with the hypoxia pathway, and is upregulated in response to Hypoxia-inducible factors. It is also overexpressed in cells affected by cardiac disease and tumours. MiRNA-210 in particular, has been studied for its effects in rescuing cardiac function after myocardial infarcts via the up-regulation of angiogenesis and inhibition of cardiomyocyte apoptosis.

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5'  ucc agaugc ggu agcc cug    acgcaca ug gc     c
    ||| |||||| ||| |||| |||    ||||||| || ||      
3'  agg ucuacg cca ucgg gac    ugcgugu ac cg     u
   a   a      a   a    c   agug       c  -  uaaaa 
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Genome context
Coordinates (Xenopus_tropicalis_v9.1; GCA_000004195.3) Overlapping transcripts
chr4: 39569264-39569354 [-]
Database links

Mature sequence xtr-miR-210

Accession MIMAT0003624

56 - 


 - 77

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Evidence by similarity; MI0001379
Predicted targets